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冠状动脉瘤导致的猝死:川崎病的晚期并发症。

Sudden death caused by coronary artery aneurysms: a late complication of Kawasaki disease.

作者信息

Wreford F S, Conradi S E, Cohle S D, Lie J T, Dana S E, Puri S

机构信息

Blodgett Memorial Medical Center, Grand Rapids, MI.

出版信息

J Forensic Sci. 1991 Jan;36(1):51-9.

PMID:2007880
Abstract

The authors describe three cases (two blacks and one Latin American) of sudden death caused by late complications of Kawasaki disease (mucocutaneous lymph node syndrome). At autopsy each heart contained multiple coronary artery aneurysms with luminal stenosis caused by intimal hyperplasia and thrombi. Although virtually all fatal cases of Kawasaki disease occur within six months of the onset of symptoms, there have been other reported deaths up to 14 years after the acute illness. The coronary artery aneurysms of Kawasaki disease may persist and cause death years after the acute illness.

摘要

作者描述了3例(2例黑人、1例拉丁美洲人)因川崎病(黏膜皮肤淋巴结综合征)晚期并发症导致的猝死病例。尸检时,每例心脏均有多个冠状动脉瘤,伴有因内膜增生和血栓形成导致的管腔狭窄。虽然几乎所有川崎病致死病例都发生在症状出现后的6个月内,但也有其他报道称在急性病发作后长达14年出现死亡病例。川崎病的冠状动脉瘤可能持续存在,并在急性病多年后导致死亡。

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