Kristensen I B, Kristensen B O
Institute of Forensic Medicine, University of Aarhus, Denmark.
Int J Legal Med. 1994;106(5):277-80. doi: 10.1007/BF01225421.
Kawasaki disease primarily affects children below 5 years of age, and fatal coronary complications usually occur within 6-12 months following the acute illness. We report 2 unusual fatal cases of thrombosed coronary artery aneurysms. The first case was an 11-year-old boy, who died suddenly 2 months after the acute illness. He had a classical clinical picture, but was misdiagnosed. The second case was a 29-year-old man without history of recent febrile episodes or cardiac symptoms. Both subjects fulfilled the stage 4 criteria of Kawasaki disease (healing stage) with extensive old myocardial damage. The cases illustrate the great variation in the clinical picture of Kawasaki disease. Teenagers can also be affected, and extensive myocardial damage may be asymptomatic for many years.
川崎病主要影响5岁以下儿童,致命的冠状动脉并发症通常在急性疾病发作后的6至12个月内发生。我们报告2例罕见的冠状动脉瘤血栓形成致死病例。第一例是一名11岁男孩,在急性疾病发作2个月后突然死亡。他有典型的临床表现,但被误诊。第二例是一名29岁男性,近期无发热病史或心脏症状。两名患者均符合川崎病4期标准(恢复期),伴有广泛的陈旧性心肌损伤。这些病例说明了川崎病临床表现的巨大差异。青少年也可能受到影响,广泛的心肌损伤可能多年无症状。