Department of Childrens' Heart Center, BAYI Children's Hospital, General Hospital of Beijing Military Command, Beijing 100700, China.
Chin Med J (Engl). 2009 Oct 5;122(19):2335-8.
The fenestration function is by allowing a right-to-left shunt resulting in an increased cardiac index, associated with mild arterial oxygen desaturation. Subsequent transcatheter fenestration closure can be performed after haemodynamic assessment. The purpose of this study was to compare the outcomes of extracardiac connection (EC) with or without fenestration.
Ninety-five consecutive patients diagnosed with univentricular heart disease underwent EC using Gore-Tax conduits at the Department of Children's Heart Center, Justus-Liebig-University Giessen Germany from June 1996 to July 2007. According to EC with or without fenestration, the patients were assigned to two groups (group A with fenestration and group B without fenestration). Mortality, effusions, postoperative mean pulmonary artery pressure, postoperative oxygen saturation, postoperative thrombosis, postoperative neurological problems, and the postoperative loss of sinus rhythm were compared. In group A, 23 patients had fenestration closed interventionally after a mean time of 20-22 months.
Mortality and postoperative mean pulmonary artery pressure in group B (3 and (15.1 +/- 3.4) mmHg, respectively) were significantly higher than group A (0 and (13.2 +/- 2.8) mmHg, respectively). Postoperative oxygen saturation, postoperative thrombosis, postoperative neurological problems, and the postoperative loss of sinus rhythm did not differ between cohorts.
Fenestrating an extracardiac tunnel seems to improve acute postoperative mortality by rising cardiac output. The induced right-to-left shunt shows no morbidity postoperatively. If a stabilized chronic hemodynamic situation is achieved, an interventional closure of the fenestration can be performed to advance the arterial saturation and improve the exercise tolerance of the patients.
开窗功能通过允许右向左分流,从而导致心输出量增加,伴有轻度动脉血氧饱和度降低。随后可在血流动力学评估后进行经导管开窗关闭。本研究的目的是比较有无外腔连接(EC)开窗的结果。
1996 年 6 月至 2007 年 7 月,德国吉森市 Justus-Liebig-University 儿童心脏中心的 95 例诊断为单心室心脏病的连续患者使用 Gore-Tax 导管进行 EC。根据是否有 EC 开窗,将患者分为两组(A 组有开窗,B 组无开窗)。比较死亡率、胸腔积液、术后平均肺动脉压、术后氧饱和度、术后血栓形成、术后神经系统问题和窦性节律丧失。在 A 组中,23 例患者在平均 20-22 个月后接受介入性关闭开窗。
B 组(分别为 3 例和(15.1 +/- 3.4)mmHg)的死亡率和术后平均肺动脉压明显高于 A 组(分别为 0 例和(13.2 +/- 2.8)mmHg)。两组术后氧饱和度、术后血栓形成、术后神经系统问题和窦性节律丧失无差异。
在体外隧道开窗似乎可以通过增加心输出量来改善急性术后死亡率。诱导的右向左分流术后没有并发症。如果达到稳定的慢性血液动力学状态,可以进行介入性关闭开窗,以提高动脉饱和度并提高患者的运动耐量。