Jiang Jin-yan, Zhu Zhi-yu, Geng Ning, Yang Ming-zhong, Xia Li-li, Cheng Yu
Department of Oral Pathology, Sichuan University, Chengdu 610041, China.
Zhonghua Kou Qiang Yi Xue Za Zhi. 2009 Oct;44(10):614-8.
To report eight cases of central mucoepidermoid carcinoma of the jaws (CMCJ) and to analyze its clinical and pathological features.
Eight cases of central mucoepidermoid carcinoma were diagnosed between 1989 and 2008. The clinical manifestation, radiological and histopathological changes were analyzed.
The mean age of this group of patients was 43.3 years, with 5 male and 3 female. Seven cases occurred in mandible, mainly in the molar, angle and ramus areas, and one in maxilla. The first complain usually was local swelling, pain or paraesthesia of the jaw and loosening and pain of the tooth. X-ray displayed unilocular or multilocular radiolucent lesion with distinct or ill-distinct border, and the light microscopic findings were similar to the mucoepidermoid carcinoma originated in the salivary gland.
To diagnose a CMCJ, it's necessary to synthetically analyze the case history, clinical examination, radiological and histopathological features. The treatment is wide local resection. Selective neck dissection and radiochemotherapy may improve curative effect and prognosis.
报告8例颌骨中央型黏液表皮样癌（CMCJ），并分析其临床及病理特征。
1989年至2008年间诊断出8例中央型黏液表皮样癌。对其临床表现、影像学及组织病理学变化进行分析。
该组患者的平均年龄为43.3岁，男性5例，女性3例。7例发生在下颌骨，主要位于磨牙区、角部及升支区，1例发生在上颌骨。首发症状通常为颌骨局部肿胀、疼痛或感觉异常，以及牙齿松动和疼痛。X线表现为单房或多房透射性病变，边界清晰或不清晰，光镜下表现与起源于唾液腺的黏液表皮样癌相似。
诊断CMCJ时，有必要综合分析病史、临床检查、影像学及组织病理学特征。治疗方法为广泛局部切除。选择性颈清扫术及放化疗可能提高疗效及预后。
