癌症中Id-1的表达与预后：抗体重要吗？ - Suppr

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Id-1 expression and prognosis in cancer: do antibodies matter?

作者信息

Gil-Bazo Ignacio, Ponz-Sarvisé Mariano, Panizo-Santos Angel, Calvo Alfonso

出版信息

Clin Transl Oncol. 2010 Jan;12(1):69. doi: 10.1007/s12094-010-0470-3.

DOI:10.1007/s12094-010-0470-3

PMID:20080475

Abstract

摘要

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本文引用的文献

Angiogenesis and ovarian cancer.

Clin Transl Oncol. 2009 Sep;11(9):564-71. doi: 10.1007/s12094-009-0406-y.

ID genes mediate tumor reinitiation during breast cancer lung metastasis.

Proc Natl Acad Sci U S A. 2007 Dec 4;104(49):19506-11. doi: 10.1073/pnas.0709185104. Epub 2007 Nov 28.

Id1 restrains myeloid commitment, maintaining the self-renewal capacity of hematopoietic stem cells.

Proc Natl Acad Sci U S A. 2007 Jan 23;104(4):1260-5. doi: 10.1073/pnas.0607894104. Epub 2007 Jan 16.

Reassessment of id1 protein expression in human mammary, prostate, and bladder cancers using a monospecific rabbit monoclonal anti-id1 antibody.

Cancer Res. 2006 Nov 15;66(22):10870-7. doi: 10.1158/0008-5472.CAN-06-2643.

Id-1 modulates senescence and TGF-beta1 sensitivity in prostate epithelial cells.

Biol Cell. 2006 Sep;98(9):523-33. doi: 10.1042/BC20060026.

Inactivation of Id-1 in prostate cancer cells: A potential therapeutic target in inducing chemosensitization to taxol through activation of JNK pathway.

Int J Cancer. 2006 Apr 15;118(8):2072-81. doi: 10.1002/ijc.21592.

The association of Id-1, MIF and GSTpi with acquired drug resistance in hormone independent prostate cancer cells.

Oncol Rep. 2005 May;13(5):983-8.

Angiogenesis impairment in Id-deficient mice cooperates with an Hsp90 inhibitor to completely suppress HER2/neu-dependent breast tumors.

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Id-1 is not expressed in the luminal epithelial cells of mammary glands.

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Level of Id-1 protein expression correlates with poor differentiation, enhanced malignant potential, and more aggressive clinical behavior of epithelial ovarian tumors.

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