Walter Reed Army Medical Center, Washington, DC, USA.
Spine (Phila Pa 1976). 2010 Jan 15;35(2):177-81. doi: 10.1097/BRS.0b013e3181c77f8c.
Retrospective review.
To compare the incidence of and risk factors for proximal junctional kyphosis (PJK) in adolescent idiopathic scoliosis (AIS) following posterior spinal fusion using hook, pedicle screw, or hybrid constructs.
Proximal junctional kyphosis is a recently recognized phenomenon in adults and adolescents after AIS surgery. The postoperative effect on PJK with the use of hooks, hybrid constructs, or screws has not been compared in a multicenter study to date.
From a multicenter database, the preoperative and 2-year follow-up radiographic measurements from 283 patients with AIS treated with posterior spinal fusion using hooks (group 1, n = 51), hybrid constructs (group 2, n = 177), pedicle screws (group 3, n = 37), and pedicle screws with hooks only at the top level (group 4, n = 18) were compared.
The average proximal level kyphosis at 2 years after surgery was 8.2 degrees (range -1 to 18) in the all screw constructs, representing a significant increase when compared with hybrid and all hook constructs, 5.7 degrees (P = 0.02) and 5.0 degrees (P = 0.014), respectively. Conversely, average postoperative T5-T12 kyphosis was significantly less (P = 0.016) in the screw group compared with the all hook group. Of potential interest, but currently not statistically significant, was the trend towards a decrease in proximal kyphosis in constructs with all pedicle screws except hooks at the most cephalad segment, 6.4 degrees . The incidence of PJK (assuming PJK is a kyphotic deformity greater than 15 degrees ) was 0% in group 1, 2.3% in group 2, 8.1% in group 3, and 5.6% in group 4 (P = 0.18). Patients with PJK had an increased body mass index compared with those who did not meet criteria for PJK (P = 0.013).
Adjacent level proximal kyphosis was significantly increased with pedicle screws, but the clinical significance of this is unclear. A potential solution is the substitution of hooks at the upper-instrumented vertebrae, but further investigation is required.
回顾性研究。
比较使用钩、椎弓根螺钉或混合结构后路脊柱融合治疗青少年特发性脊柱侧凸(AIS)后近端交界性后凸(PJK)的发生率和危险因素。
PJK 是成人和青少年 AIS 手术后新出现的现象。迄今为止,还没有多中心研究比较使用钩、混合结构或螺钉对 PJK 的术后影响。
从多中心数据库中,比较了 283 例 AIS 患者的术前和 2 年随访影像学测量值,这些患者接受了后路脊柱融合术,使用钩(第 1 组,n = 51)、混合结构(第 2 组,n = 177)、椎弓根螺钉(第 3 组,n = 37)和仅在上位水平使用钩的椎弓根螺钉(第 4 组,n = 18)。
与混合和全钩结构相比,所有螺钉结构术后 2 年近端水平后凸平均增加 8.2 度(范围 -1 至 18),差异有统计学意义,分别为 5.7 度(P = 0.02)和 5.0 度(P = 0.014)。相反,与全钩组相比,螺钉组术后 T5-T12 后凸明显减少(P = 0.016)。有趣的是,目前尚未具有统计学意义,但有趋势表明,除最头端节段外,所有椎弓根螺钉结构的近端后凸减少 6.4 度。PJK 的发生率(假设 PJK 是大于 15 度的后凸畸形)为 0%(第 1 组)、2.3%(第 2 组)、8.1%(第 3 组)和 5.6%(第 4 组)(P = 0.18)。与不符合 PJK 标准的患者相比,患有 PJK 的患者体重指数更高(P = 0.013)。
椎弓根螺钉会显著增加邻近节段近端后凸,但这一结果的临床意义尚不清楚。一种潜在的解决方案是在上位器械化椎体中使用钩,但需要进一步研究。