Department of Radiology, The Netherlands Azienda Ospedaliero-Universitaria di Parma, Non-Invasive Cardiovascular Imaging, Piastra Tecnica, Piano 0, Via Gramsci 14, 43100 Parma, Italy.
J Cardiovasc Med (Hagerstown). 2009 Nov;10(11):821-6. doi: 10.2459/JCM.0b013e32832e8ce5.
In the absence of a fixed relationship between plaque vulnerability and flow-limiting stenosis, alternative morphological expressions exist that could predict the liability of coronary lesions to rapidly progress or rupture, causing acute coronary syndromes. Modern multidetector computed tomography technology is capable of noninvasively detecting lesion location, attenuation, remodeling and calcification pattern, which may be considered as surrogate morphological markers of vulnerability and could contribute to increase the prognostic value of individual coronary plaque burden.
在斑块易损性与限制血流的狭窄之间不存在固定关系的情况下，存在其他形态学表现，这些表现可能预测冠状动脉病变迅速进展或破裂的可能性，导致急性冠状动脉综合征。现代多排螺旋计算机断层扫描技术能够无创地检测病变部位、衰减、重构和钙化模式，这些可能被视为易损性的替代形态学标志物，并有助于提高个体冠状动脉斑块负担的预后价值。
