Peeters P, Keirse K, Verbist J, Deloose K, Bosiers M
Department of Cardiovascular and Thoracic Surgery, Imelda Hospital, Bonheiden, Belgium.
J Cardiovasc Surg (Torino). 2010 Feb;51(1):121-4.
Several limitations inherent to the implantation of a metallic device, such as the occurrence of in-stent re-stenosis, in an arterial lumen intuitively explain the interest for developing bio-absorbable stents. Two main types of bio-absorbable stents currently exist: polymer stents and metallic stents. To date, no studies with bio-absorbable stents have been conducted in the superficial femoral artery (SFA). Because of their strut thickness and lack of radial force, polymer stents are no good candidates for endovascular use. Absorbable metal stents (AMS) do have the potential to perform well for artery treatment, although current evidence from in-human coronary and infrapopliteal studies yield unsatisfactory results. Drastic technological improvements are mandatory before AMS can be considered for every day practice. Yet, it is our belief that further development of other metal and non-metal bio-absorbable stents, with or without drug-coating, may lead to the creation of the ultimate SFA stent.
金属装置植入存在一些固有的局限性，比如动脉管腔内支架内再狭窄的发生，这直观地解释了研发生物可吸收支架的意义所在。目前存在两种主要类型的生物可吸收支架：聚合物支架和金属支架。迄今为止，尚未在股浅动脉（SFA）中开展过生物可吸收支架的研究。由于聚合物支架的支柱厚度及缺乏径向力，它们并非血管内使用的理想选择。可吸收金属支架（AMS）确实有在动脉治疗中表现良好的潜力，尽管目前来自人体冠状动脉和腘动脉以下研究的证据结果并不理想。在可吸收金属支架能够被考虑用于日常临床实践之前，必须进行重大的技术改进。然而，我们相信，进一步研发其他金属和非金属生物可吸收支架，无论有无药物涂层，都可能带来终极股浅动脉支架的诞生。
