Afon'kin V Iu, Dobretsov K G, Sipkin A V
Vestn Otorinolaringol. 2009(6):69-70.
The objective of this study was to evaluate results of the new therapeutic modality for the management of chronic neurosensory loss of hearing based on the use of caviton. The open randomized study involved 50 patients. Criteria for the efficiency of therapy included the patients' complaints, self-evaluation of tympanophonia based on the visual-analogous scale, results of audiologic examination and Doppler ultrasound of carotid and vertebral arteries. Significant improvement of audiologic characteristics was documented in 80% of the patients; ultrasound examination showed that most of them tended to benefit from caviton therapy and reported reduction of tympanophonia. It is concluded that the new caviton dosing scheme for the treatment of neurosecretory loss of hearing is well tolerated by the patients and can be recommended for more extensive clinical application.
本研究的目的是评估基于使用卡维通(caviton)治疗慢性神经性听力损失的新治疗方式的效果。这项开放性随机研究纳入了50名患者。治疗效果的标准包括患者的主诉、基于视觉模拟量表的耳鸣自我评估、听力检查结果以及颈动脉和椎动脉的多普勒超声检查结果。80%的患者听力特征有显著改善;超声检查显示,他们中的大多数人倾向于从卡维通治疗中获益,并报告耳鸣减轻。结论是,用于治疗神经性听力损失的新卡维通给药方案患者耐受性良好,可推荐用于更广泛的临床应用。