Department of Ophthalmology, University of Minnesota, Minneapolis, MN, USA.
Surv Ophthalmol. 2010 May-Jun;55(3):290-6. doi: 10.1016/j.survophthal.2009.09.002. Epub 2010 Jan 18.
A 52-year-old man developed transient, migratory polyarthralgias in the presence of hearing loss. He then developed persistent leukocytosis and thrombocytosis. His initial transient, bilateral visual obscurations happened in context with bilateral disk edema and an enlarged blind spot. Visual symptoms progressed to vision loss and multiple branch retinal artery occlusions. It was not until later in the disease progression that gastrointestinal symptoms occurred. Electron microscopy of duodenal biopsies confirmed a diagnosis of Whipple disease.
一位 52 岁男性在出现听力损失的同时出现短暂、游走性多关节痛。随后他出现持续性白细胞增多和血小板增多。他最初的双侧一过性、双侧视盘水肿伴盲点扩大的视力模糊症状进展为视力丧失和多发性视网膜分支动脉阻塞。直到疾病进展后期才出现胃肠道症状。十二指肠活检的电子显微镜检查证实了 Whipple 病的诊断。
