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淋巴瘤化疗后发生胃脾瘘。

Gastrosplenic fistula following chemotherapy for lymphoma.

作者信息

Moghazy K M

机构信息

Department of Radiology, Medical School, King Faisal University, Saudi Arabia.

出版信息

Gulf J Oncolog. 2008 Jan(3):64-7.

PMID:20084800
Abstract

Gastrosplenic fistula resulting from erosion of a primary splenic lymphoma is a very rare cause of massive upper gastrointestinal hemorrhage as compared to benign peptic ulcer disease, gastric Crohn's disease, gastric adenocarcinoma, and primary gastric and splenic lymphomas. This hemorrhage can be successfully managed by splenic artery embolization, followed by splenectomy and gastric resection. A 50-year-old patient developed a gastrosplenic fistula during a course of chemotherapy for differentiated histiocytic lymphoma. The fistula was demonstrated by CT scan with oral contrast. The fistula was followed endoscopically and noted to have closed spontaneously with confirmed closure at laparotomy. The clinical management of this complication is discussed, and the literature pertaining to this rare condition is reviewed.

摘要

与良性消化性溃疡病、胃克罗恩病、胃腺癌以及原发性胃和脾淋巴瘤相比,原发性脾淋巴瘤侵蚀导致的胃脾瘘是大量上消化道出血的非常罕见的原因。这种出血可通过脾动脉栓塞成功处理,随后进行脾切除术和胃切除术。一名50岁患者在分化型组织细胞淋巴瘤化疗过程中发生胃脾瘘。口服对比剂的CT扫描显示了瘘管。通过内镜对瘘管进行随访,发现其已自行闭合,剖腹手术证实闭合。本文讨论了该并发症的临床处理,并复习了有关这种罕见情况的文献。

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J Med Case Rep. 2024 Mar 7;18(1):136. doi: 10.1186/s13256-024-04441-2.
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