Meguro Toshinari, Sasaki Tatsuya, Haruma Jun, Tanabe Tomoyuki, Muraoka Kenichiro, Terada Kinya, Hirotsune Nobuyuki, Nishino Shigeki
Department of Neurological Surgery, Hiroshima City Hospital, Naka-ku, Hiroshima, Japan.
No Shinkei Geka. 2010 Jan;38(1):41-5.
A case of arterial stenosis after coil migration in intracranial aneurysm embolization is presented. A 51-year-old woman suffered sudden onset of headache and unconsciousness. Computed tomography demonstrated diffuse subarachnoid hemorrhage and cerebral angiography disclosed a right internal carotid artery (ICA) bifurcation aneurysm and a right ICA-anterior choroidal artery aneurysm. The aneurysms were treated by endovascular embolization with Guglielmi detachable coils. During the embolization procedure of the ICA bifurcation aneurysm, a coil strand detached in the sac had migrated into the ICA. We did not retrieve the migrated coil, because the free coil strand was stable in the ICA and did not cause distal flow reduction. The patient suffered vasospasm of the right ICA and underwent intra-arterial infusion of fasudil hydrochloride and percutaneous transluminal angioplasty of the ICA on day 9. The patient experienced infarction in the territory of the right anterior cerebral artery area and needed a ventriculo-peritoneal shunt for hydrocephalus. The patient was discharged with mild right hemiparesis. Follow-up angiography after six months revealed right ICA and middle cerebral artery stenosis, but the free strand of the migrated coil had not moved in the right ICA. We suspect that the coil strand might have induced thrombosis or intimal hyperplasia of the proximal M1 segment and right ICA. Although late stenosis of the parent artery might be rare, it should be recognized as a long term complication of a migrated free coil strand in the endovascular treatment of intracranial aneurysms.
本文报告一例颅内动脉瘤栓塞术后弹簧圈移位导致动脉狭窄的病例。一名51岁女性突发头痛和昏迷。计算机断层扫描显示弥漫性蛛网膜下腔出血,脑血管造影显示右侧颈内动脉(ICA)分叉处动脉瘤和右侧颈内动脉-脉络膜前动脉动脉瘤。采用 Guglielmi 可脱性弹簧圈进行血管内栓塞治疗这些动脉瘤。在ICA分叉处动脉瘤的栓塞过程中,瘤腔内的一根弹簧圈丝断裂并移位至ICA。由于游离的弹簧圈丝在ICA内稳定且未导致远端血流减少,我们未取出移位的弹簧圈。患者在第9天出现右侧ICA血管痉挛,接受了动脉内注射盐酸法舒地尔及ICA经皮腔内血管成形术。患者右侧大脑前动脉供血区发生梗死,因脑积水需要行脑室-腹腔分流术。患者出院时遗留轻度右侧偏瘫。6个月后的随访血管造影显示右侧ICA和大脑中动脉狭窄,但移位弹簧圈的游离丝在右侧ICA内未移动。我们怀疑弹簧圈丝可能诱发了近端M1段和右侧ICA的血栓形成或内膜增生。虽然载瘤动脉的晚期狭窄可能少见,但在颅内动脉瘤血管内治疗中,应将其视为移位游离弹簧圈丝的一种长期并发症。