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[硫-35的致突变和致癌作用]

[The mutagenic and carcinogenic effects of sulfur-35].

作者信息

Monakhov A S

出版信息

Radiobiologiia. 1991 Jan-Feb;31(1):139-42.

PMID:2008514
Abstract

In experiments with metaphase plates from blood lymphocytes, conducted during rats' lifetime, a study was made of the mutagenic effect of 35S. Various tumors were diagnosed in the experimental animals after their death. The competitive analysis of the number of stable cytogenetic changes in lymphocytes of the experimental animals at the remote times and tumor occurrence has revealed a highly positive correlation between these indices. Both effects were severest at the highest absorbed 35S dose of less than 10 cGy.

摘要

在大鼠生命周期内进行的血淋巴细胞中期板实验中,对35S的诱变作用进行了研究。实验动物死后诊断出各种肿瘤。对实验动物淋巴细胞中稳定细胞遗传学变化数量在较长时间与肿瘤发生情况的竞争性分析表明,这些指标之间存在高度正相关。在吸收剂量最高小于10 cGy的35S时,这两种效应最为严重。

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