Kayser L, Gravesen H S
Købenshavns Amts Sygehus i Herlev, klinisk kemisk afdeling.
Ugeskr Laeger. 1991 Mar 4;153(10):719-21.
Hypophosphataemia is a potentially dangerous condition which may be present but unrecognized in prolonged periods. The incidence of hypophosphataemia among patients in a Danish hospital population was determined retrospectively by registering the number of blood samples with low serum phosphate values (less than or equal to 0.6 mmol l/l) in a Danish university hospital during a period without and in a period with an open casualty department. Case reports from patients with low serum phosphate values were reviewed with the object of revealing the causes of the hypophosphataemia and possible symptoms which might be related to the hypophosphataemic condition. A total of 192 patients were found with serum phosphate values less than or equal to 0.6 mmol/l but only 15 patients with severe hypophosphataemia (serum phosphate less than or equal to 0.3 mmol/l). No relationship between the serum phosphate concentration and the symptoms could be demonstrated. The commonest causes of hypophosphataemia were gastrointestinal loss and parenteral infusion of fluids. Quoting of low serum phosphate measurement is not recommended unless this analysis has been specially requested as the majority of cases even of severe hypophosphataemia are self-limiting and do not produce symptoms.
低磷血症是一种潜在的危险状况，可能在较长时间内存在但未被识别。通过记录丹麦一家大学医院在无急诊室开放期间和有急诊室开放期间血清磷酸盐值低（小于或等于0.6毫摩尔/升）的血样数量，对丹麦医院患者群体中的低磷血症发病率进行了回顾性测定。对血清磷酸盐值低的患者的病例报告进行了审查，目的是揭示低磷血症的病因以及可能与低磷血症状况相关的症状。共发现192例患者血清磷酸盐值小于或等于0.6毫摩尔/升，但只有15例严重低磷血症患者（血清磷酸盐小于或等于0.3毫摩尔/升）。血清磷酸盐浓度与症状之间未发现关联。低磷血症最常见的病因是胃肠道丢失和胃肠外补液。除非特别要求进行此项分析，否则不建议报告低血清磷酸盐测量结果，因为即使是大多数严重低磷血症病例也是自限性的，不会产生症状。
