Inoue Madoka, Sairyo Koichi, Sakai Toshinori, Yasui Natsuo
Department of Orthopedics, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan.
J Pediatr Orthop B. 2010 May;19(3):270-5. doi: 10.1097/BPB.0b013e32833561c7.
There have been several reports about the treatments for dystrophic changes in the thoracic or lumbar spines owing to neurofibromatosis type-1. However, dystrophic changes in the cervical spine have been rarely reported. In this study, we present the case of a 13-year-old boy with severe dystrophic changes (dural ectasia) in the cervical spine owing to neurofibromatosis type-1. Although he had no neurological deficit, imaging studies revealed cervical kyphotic deformity and osteolysis of vertebral bodies. Thinning of vertebral bodies and laminae from C2 to C5 was remarkable, suggesting that the patient was at risk of suffering a spinal injury. The patient underwent cervical posterior fusion. At the 2-year follow-up examination, there was complete posterior bony fusion and no obvious progression.
已有多篇关于1型神经纤维瘤病所致胸腰椎营养不良性改变治疗的报道。然而，颈椎的营养不良性改变鲜有报道。在本研究中，我们报告了1例13岁男孩因1型神经纤维瘤病导致颈椎严重营养不良性改变（硬脊膜扩张）的病例。尽管他没有神经功能缺损，但影像学检查显示颈椎后凸畸形和椎体骨质溶解。C2至C5椎体和椎板变薄明显，提示该患者有脊髓损伤风险。该患者接受了颈椎后路融合术。在2年的随访检查中，实现了完全的后路骨性融合，且无明显进展。
