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[女性献血者的血红蛋白浓度与铁储备]

[Hemoglobin concentration and iron stores in female blood donors].

作者信息

Dalhøj J, Wiggers P

机构信息

Arvepatologisk Institut, Odense Universitet.

出版信息

Ugeskr Laeger. 1991 Feb 25;153(9):643-5.

PMID:2008755
Abstract

The blood hemoglobin concentration (B-Hb) and iron indices were measured in 1,856 consecutive female blood donors. The blood hemoglobin distribution was Gaussian except for an excess of high values. According to criteria defined by the WHO, 9.5% of the population were anemic, but using several criteria only 0.9% had iron deficiency anemia in agreement with the blood hemoglobin distribution curve. The distribution of the S-ferritin values was log Gaussian. Nearly 1/5 of female blood donors had low iron stores despite widespread use of iron supplements. The weak correlation detected between the B-Hb values and the S-ferritin level points to an increased risk of anemia in female blood donors. Regular determination of the S-ferritin level in female blood donors or extended use of iron supplements may contribute to the establishment of adequate iron stores and hence the prevention of anemia.

摘要

对1856名连续的女性献血者测量了血液血红蛋白浓度(B-Hb)和铁指标。除了高值过多外,血液血红蛋白分布呈高斯分布。根据世界卫生组织定义的标准,9.5%的人群贫血,但使用多种标准时,只有0.9%的人患有缺铁性贫血,这与血液血红蛋白分布曲线一致。血清铁蛋白(S-铁蛋白)值的分布呈对数高斯分布。尽管广泛使用铁补充剂,但近五分之一的女性献血者铁储备较低。B-Hb值与S-铁蛋白水平之间检测到的弱相关性表明女性献血者贫血风险增加。定期测定女性献血者的S-铁蛋白水平或扩大铁补充剂的使用可能有助于建立充足的铁储备,从而预防贫血。

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