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分析菲奇法在构建超度量系统发生树上祖先状态的应用。

Analyzing the fitch method for reconstructing ancestral states on ultrametric phylogenetic trees.

机构信息

Department of Mathematics, National University of Singapore, Singapore 117543, Singapore.

出版信息

Bull Math Biol. 2010 Oct;72(7):1760-82. doi: 10.1007/s11538-010-9505-8. Epub 2010 Jan 20.

Abstract

The accuracy of the Fitch method for reconstructing ancestral states on ultrametric phylogenetic trees is studied. Two recurrence relations for computing the accuracy are given here. Using these relations, we analyze the convergence of the accuracy of the Fitch method for reconstructing the root state on a complete binary tree of 2( n ) leaves as n goes to infinity, present a closed-form formula for the accuracy on ultrametric comb trees, and provide a lower bound on the accuracy on arbitrary ultrametric phylogenetic trees.

摘要

研究了菲奇方法在构建超度量系统发生树上祖先状态的准确性。本文给出了计算准确性的两个递归关系。利用这些关系,我们分析了在 n 趋于无穷大时,菲奇方法在重建 2(n)个叶子的完全二叉树上根状态的准确性的收敛性,给出了超度量梳状树上准确性的闭式公式,并为任意超度量系统发生树上的准确性提供了一个下界。

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