Akin I, Ince H, Kische S, Schneider H, Ortak J, Rehders T C, Nienaber C A, Chatterjee T
Klinikum I, Abteilung für Kardiologie, Pulmonologie, internistische Intensivmedizin, Universität Rostock.
Praxis (Bern 1994). 2010 Jan 20;99(2):107-15. doi: 10.1024/1661-8157/a000013.
The idiopathic pulmonal arterial hypertension is characterized by a chronic proliferative conversion of the pulmonary arterial vessels leading to an increase of pulmonary vascular resistance and thus resulting in right heart failure and increase mortality rate. With growing advances in understanding of the underlying pathophysiological mechanisms and the development of modern medical treatment strategies, there is a significant improvement of the overall survival rate and quality-of life. In this review we will give an overview about the current knowledge of etiology, diagnosis and management of idiopathic pulmonal arterial hypertension.
特发性肺动脉高压的特征是肺动脉血管发生慢性增殖性转变，导致肺血管阻力增加，进而引发右心衰竭并提高死亡率。随着对潜在病理生理机制认识的不断进步以及现代医学治疗策略的发展，总体生存率和生活质量有了显著改善。在本综述中，我们将概述特发性肺动脉高压的病因、诊断和管理的当前知识。
