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维生素 B6:一石二鸟?

Vitamin B6: Killing two birds with one stone?

机构信息

Washington State University, Pullman, Abelson Hall, WA 99164, USA.

出版信息

Phytochemistry. 2010 Apr;71(5-6):495-501. doi: 10.1016/j.phytochem.2009.12.015. Epub 2010 Jan 19.

DOI:10.1016/j.phytochem.2009.12.015
PMID:20089286
Abstract

Vitamin B6 comprises a group of compounds that are involved in a surprisingly high diversity of biochemical reactions. Actually, most of these reactions are co-catalyzed by a single B6 vitamer, pyridoxal 5'-phosphate, making it a crucial and versatile co-factor in many metabolic processes in the cell. In addition, it has been demonstrated in recent years that vitamin B6 has a second important function by being an effective antioxidant. Because of these two characteristics the vitamin is an interesting compound to study in plants. This review provides a brief overview and update on such important aspects like vitamin B6-dependent enzymes and known biosynthetic pathways in plants, phenotypes of plant mutants affected in vitamin B6 biosynthesis, and the potential benefits of modifying vitamin B6 content in plants.

摘要

维生素 B6 由一组化合物组成,这些化合物参与了令人惊讶的多种生化反应。实际上,这些反应中的大多数都是由单个 B6 变体,即 5'-磷酸吡哆醛共同催化的,使其成为细胞内许多代谢过程中至关重要且多功能的辅酶。此外,近年来的研究表明,维生素 B6 通过充当有效的抗氧化剂而具有第二个重要功能。由于这两个特点,维生素是研究植物的一个有趣的化合物。这篇综述简要概述和更新了植物中维生素 B6 依赖性酶和已知生物合成途径、维生素 B6 生物合成受影响的植物突变体的表型以及修饰植物中维生素 B6 含量的潜在益处等重要方面。

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