Department of Pharmacotherapy, Washington State University, Spokane, WA, 99202, USA.
Matern Child Health J. 2011 Oct;15(7):974-9. doi: 10.1007/s10995-009-0555-1.
The objective of this study was to estimate the association between residence in coal mining environments and low birth weight. We conducted a cross-sectional, retrospective analysis of the association between low birth weight and mother's residence in coal mining areas in West Virginia. Birth data were obtained from the West Virginia Birthscore Dataset, 2005-2007 (n = 42,770). Data on coal mining were from the US Department of Energy. Covariates regarding mothers' demographics, behaviors, and insurance coverage were included. We used nested logistic regression (SUDAAN Proc Multilog) to conduct the study. Mothers who were older, unmarried, less educated, smoked, did not receive prenatal care, were on Medicaid, and had recorded medical risks had a greater risk of low birth weight. After controlling for covariates, residence in coal mining areas of West Virginia posed an independent risk of low birth weight. Odds ratios for both unadjusted and adjusted findings suggest a dose-response effect. Adjusted findings show that living in areas with high levels of coal mining elevates the odds of a low-birth-weight infant by 16%, and by 14% in areas with lower mining levels, relative to counties with no coal mining. After covariate adjustment, the persistence of a mining effect on low-birth-weight outcomes suggests an environmental effect resulting from pollution from mining activities. Air and water quality assessments have been largely missing from mining communities, but the need for them is indicated by these findings.
这项研究的目的是评估居住在煤矿环境与低出生体重之间的关联。我们对西弗吉尼亚州煤矿地区母亲居住与低出生体重之间的关系进行了横断面、回顾性分析。出生数据来自于 2005 年至 2007 年的西弗吉尼亚州出生评分数据集(n = 42770)。煤矿数据来自美国能源部。研究纳入了母亲人口统计学、行为和保险覆盖情况的相关变量。我们使用嵌套逻辑回归(SUDAAN Proc Multilog)进行研究。年龄较大、未婚、受教育程度较低、吸烟、未接受产前护理、参加医疗补助计划且有医疗风险记录的母亲,低出生体重的风险更高。在控制了混杂因素后,居住在西弗吉尼亚州的煤矿地区会增加低出生体重的风险。未经调整和调整后的发现的比值比都表明存在剂量-反应关系。调整后的发现表明,与没有煤矿的县相比,居住在煤矿水平较高地区的母亲所生的低体重儿的几率增加了 16%,而居住在煤矿水平较低地区的母亲所生的低体重儿的几率增加了 14%。在进行了混杂因素调整后,煤矿对低出生体重结果的持续影响表明存在由煤矿活动造成的污染引起的环境影响。煤矿社区的空气质量和水质评估在很大程度上被忽视了,但这些发现表明了进行此类评估的必要性。