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酶联免疫吸附测定法评估墨西哥的二噁英类土壤污染。

Assessment of dioxin-like soil contamination in Mexico by enzyme-linked immunosorbent assay.

机构信息

Centro de Investigación en Genética y Ambiente, Universidad Autónoma de Tlaxcala, Km. 10.5 Autopista San Martín-Tlaxcala, CP 90120 Ixtacuixtla, Tlax., Mexico.

出版信息

Arch Environ Contam Toxicol. 2010 May;58(4):918-26. doi: 10.1007/s00244-009-9422-8. Epub 2009 Nov 29.

Abstract

In this work, we describe the results of a preliminary soil assessment program for the detection of dioxins at different sites in Mexico performed by immunoassay. We studied five different sectors considered relevant sources of dioxins: Anaversa and Tekchem industrial areas where organochlorine pesticides were manufactured and released by accidental explosions, secondary smelters, brick kilns, and rural dwellings. In the context of the Agency for Toxic Substances and Disease Registry (ATSDR) guidelines, only the brick kilns sites can be considered as low-risk areas. The dioxin concentrations detected in the vicinity of the Anaversa and Tekchem chemical plants and secondary smelters exceed the screening level of 0.05 ppb set by the ATSDR, and therefore further site-specific studies are needed. The dioxin levels found in all soot samples from indigenous dwellings where wood is used for indoor cooking were above the evaluation level. Considering that the studied areas are representative examples of dioxin sources in less developed countries, our work demonstrates the useful application of dioxin immunoassays as a tool for dioxin screening for environmental assessment programs in developing countries.

摘要

在这项工作中,我们描述了使用免疫测定法在墨西哥不同地点进行的初步土壤评估计划的结果,该计划旨在检测二恶英。我们研究了五个不同的被认为是二恶英主要来源的领域:Anaversa 和 Tekchem 工业区,这些地区曾生产和意外爆炸释放过有机氯农药;二次熔炼厂、砖窑和农村住宅。根据毒物和疾病登记署 (ATSDR) 的指导方针,只有砖窑场可以被认为是低风险区域。在 Anaversa 和 Tekchem 化工厂以及二次熔炼厂附近检测到的二恶英浓度超过了 ATSDR 设定的 0.05 ppb 的筛选水平,因此需要进行进一步的特定地点研究。在所有使用木材进行室内烹饪的土着住宅的烟尘样本中发现的二恶英含量均高于评估水平。考虑到研究区域是欠发达国家中二恶英来源的代表性例子,我们的工作表明,二恶英免疫测定法作为发展中国家环境评估计划中二恶英筛选的工具具有很好的应用前景。

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