Division of Endocrine Surgery, Department of Surgery, New York University Langone Medical Center, New York, NY, USA.
Head Neck. 2011 Jun;33(6):917-9. doi: 10.1002/hed.21339. Epub 2010 Jan 20.
Parathyroid lipoadenoma is an uncommon tumor that may be difficult to diagnose on intraoperative frozen section. Intraoperative parathyroid hormone (PTH) measurement is useful in assessing the adequacy of parathyroidectomy. This case demonstrates the value of intraoperative PTH measurement in recognizing a parathyroid lipoadenoma.
A case of a 62-year-old woman with primary hyperparathyroidism in which intraoperative PTH measurement helped confirm the diagnosis of parathyroid lipoadenoma is presented.
In patients with primary hyperparathyroidism, a significant decrease in intraoperative PTH confirms that an enlarged parathyroid with normal to low cellularity containing abundant fat is a lipoadenoma and that further exploration is not necessary.
甲状旁腺脂腺瘤是一种不常见的肿瘤,在术中冷冻切片检查时可能难以诊断。术中甲状旁腺激素(PTH)测量有助于评估甲状旁腺切除术的充分性。本病例展示了术中 PTH 测量在识别甲状旁腺脂腺瘤中的价值。
报告了一例 62 岁女性原发性甲状旁腺功能亢进症患者,术中 PTH 测量有助于确认甲状旁腺脂腺瘤的诊断。
在原发性甲状旁腺功能亢进症患者中,术中 PTH 的显著降低证实,增大的甲状旁腺细胞正常或低,含有丰富的脂肪,是一个脂腺瘤,不需要进一步探查。