Adja E Akaffou, Dick F Amon-Tanoh, N'guessan R
Service de Néonatalogie – CHU de Yopougon, 21 BP 632 Abidjan 21, Côte d’Ivoire.
Mali Med. 2009;24(3):36-9.
Malaria is rare at the newborn child's, even in zone of endemic disease, so that its research is not systematic at this age. Our study aims to describe the profile of the malaria during the neonatal period.
The retrospective and descriptive study, concerned the files of the newborn children hospitalized from 2005/02/01 till 2006/03/31, in the department of Neonatology at the teaching hospital of Yopougon in Abidjan û Côte d'Ivoire. The criteria of inclusion were fever, associated or not with other symptoms and positive thick drop and or blood smear. The criterion of exclusion was the positivity of the biological explorations for infection. The studied parameters took into account epidemiology, symptomatology, biology and therapeutics.
Prevalence of neonatal malaria was 0.98 per cent (6/615) according to our study. Except the fever which was a criterion of inclusion, the paleness was the dominant symptom. Four of our patients had a history of blood transfusion and 3 among these had a postnatal severe malaria, with highest parasitemia and lowest rates of haemoglobin. Quinine was the most used treatment.
It is important in zone of endemic malaria disease, to make at the newborn child's, often and easily, thick drop and blood smear, especially when there is a history of blood transfusion.
新生儿疟疾较为罕见,即便在疟疾流行地区也是如此,因此在这个年龄段对其研究并不系统。我们的研究旨在描述新生儿期疟疾的特征。
这项回顾性描述性研究涉及2005年2月1日至2006年3月31日在科特迪瓦阿比让约普贡教学医院新生儿科住院的新生儿病历。纳入标准为发热,无论是否伴有其他症状,以及厚血滴和/或血涂片检查呈阳性。排除标准为感染相关生物学检查呈阳性。所研究的参数包括流行病学、症状学、生物学和治疗学方面。
根据我们的研究,新生儿疟疾患病率为0.98%(6/615)。除发热作为纳入标准外,面色苍白是主要症状。我们的4例患者有输血史,其中3例患有产后重症疟疾,其寄生虫血症最高,血红蛋白水平最低。奎宁是最常用的治疗药物。
在疟疾流行地区,对新生儿经常且容易地进行厚血滴和血涂片检查很重要,尤其是在有输血史的情况下。