From the Department of Maternal and Child Health, Boston University School of Public Health; the Obesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care; and the Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts.
Obstet Gynecol. 2010 Feb;115(2 Pt 1):357-364. doi: 10.1097/AOG.0b013e3181cbd5f5.
To estimate changes over time in birth weight for gestational age and in gestational length among term singleton neonates born from 1990 to 2005.
We used data from the U.S. National Center for Health Statistics for 36,827,828 singleton neonates born at 37-41 weeks of gestation, 1990-2005. We examined trends in birth weight, birth weight for gestational age, large and small for gestational age, and gestational length in the overall population and in a low-risk subgroup defined by maternal age, race or ethnicity, education, marital status, smoking, gestational weight gain, delivery route, and obstetric care characteristics.
In 2005, compared with 1990, we observed decreases in birth weight (-52 g in the overall population, -79 g in a homogenous low-risk subgroup) and large for gestational age birth (-1.4% overall, -2.2% in the homogenous subgroup) that were steeper after 1999 and persisted in regression analyses adjusted for maternal and neonate characteristics, gestational length, cesarean delivery, and induction of labor. Decreases in mean gestational length (-0.34 weeks overall) were similar regardless of route of delivery or induction of labor.
Recent decreases in fetal growth among U.S., term, singleton neonates were not explained by trends in maternal and neonatal characteristics, changes in obstetric practices, or concurrent decreases in gestational length.
III.
评估 1990 年至 2005 年间足月单胎新生儿的胎龄相关出生体重和妊娠期的变化趋势。
我们使用了美国国家卫生统计中心的数据,纳入了 1990 年至 2005 年间 36827828 名孕 37-41 周的足月单胎新生儿。我们观察了总体人群以及根据母亲年龄、种族或民族、教育程度、婚姻状况、吸烟状况、孕期体重增加、分娩方式和产科护理特征定义的低危亚组中出生体重、胎龄相关出生体重、小于胎龄儿和大于胎龄儿以及妊娠期的变化趋势。
与 1990 年相比,2005 年我们观察到出生体重(总体人群下降 52g,同质低危亚组下降 79g)和大于胎龄儿出生比例(总体人群下降 1.4%,同质亚组下降 2.2%)下降,1999 年后下降趋势更为陡峭,并在调整了母亲和新生儿特征、妊娠期、剖宫产和引产等因素后仍持续存在。无论分娩方式或引产与否,平均妊娠期的缩短(总体人群减少 0.34 周)都相似。
美国足月单胎新生儿近期的胎儿生长下降不能用母婴特征、产科实践变化或同期妊娠期缩短来解释。
III 级。