Neuroblastoma-specific expression of potential therapeutics cannot be achieved using a promoter region of the NCX (TLX2) gene.
作者信息
Tivnan A, Stallings R L
出版信息
Cancer Gene Ther. 2010 May;17(5):373-4. doi: 10.1038/cgt.2009.90. Epub 2010 Jan 22.
Abstract
摘要
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Neuroblastoma-specific expression of potential therapeutics cannot be achieved using a promoter region of the NCX (TLX2) gene.使用NCX（TLX2）基因的启动子区域无法实现潜在治疗药物的神经母细胞瘤特异性表达。
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MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells.微小RNA-34a通过诱导神经母细胞瘤细胞凋亡发挥潜在的肿瘤抑制作用。
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Differential patterns of microRNA expression in neuroblastoma are correlated with prognosis, differentiation, and apoptosis.神经母细胞瘤中微小RNA表达的差异模式与预后、分化及凋亡相关。
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10
Ncx, a Hox11 related gene, is expressed in a variety of tissues derived from neural crest cells.
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