Chen Jialong, Li Quanli, Chen Junying, Huang Nan
College of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2009 Dec;26(6):1380-3.
Restenosis and thrombus at the site of implanting cardiovascular devices remains a significant problem in the practice of interventional cardiology. Recently, lots of studies reveal that endothelial impairment was considered as one of the most important mechanisms contributing to restenosis. The method of accelerating endothelial regeneration at the injury site could prevent restenosis and thrombus, so such methods are of importance for improving the effectiveness of interventional therapy for atherosclerosis. This paper summarized the progress in researches in-vivo re-endothelialization at the site of intravascular stent.
在心血管装置植入部位出现的再狭窄和血栓形成仍是介入心脏病学实践中的一个重大问题。最近,大量研究表明,内皮损伤被认为是导致再狭窄的最重要机制之一。在损伤部位加速内皮再生的方法可以预防再狭窄和血栓形成,因此这些方法对于提高动脉粥样硬化介入治疗的有效性具有重要意义。本文总结了血管内支架部位体内再内皮化的研究进展。