Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Dyrlaegevej 16, 1870 Frederiksberg C, Denmark.
Acta Vet Scand. 2010 Jan 22;52(1):6. doi: 10.1186/1751-0147-52-6.
The Danish Veterinary Cancer Registry (DVCR) was established in May 2005 to gather information about neoplasms in the Danish dog and cat populations. Practitioners from more than 60 clinics throughout Denmark have submitted data on these species. The objectives of the current study were, with a special focus on mast cell tumours (MCT) to investigate the occurrence, gender distribution, biological behaviour, locations, types, the diagnostic method used and treatment of skin neoplasms in dogs based on information reported to the DVCR.
From May 15th 2005 through February 29th 2008, reports on a total of 1,768 canine cases of neoplasia in the skin, subcutis or adnexa were submitted.) Of these, 765 cases (43%) were confirmed by cytology or histopathology.
The majority of dogs had a benign neoplasm (66%) while 21% were cases of malignant neoplasia. The most commonly encountered malignant neoplasms were MCT and soft tissue sarcomas and for benign neoplasms, lipomas and histiocytomas were the most common. The location of the neoplasms were primarily in the cutis, subcutis or in the perianal region. The occurrence, gender distribution, biological behaviour and location of canine skin neoplasias in Denmark were similar to earlier reports, although some national variations occurred. A correlation between grade of MCT and the proportion of cases treated surgically was observed.
Population based cancer registries like the DVCR are of importance in the collection of non-selected primary information about occurrence and distribution of neoplasms. The DVCR provides detailed information on cases of skin neoplasms in dogs and may serve as a platform for the study of sub-sets of neoplastic diseases (e.g. MCT) or subgroups of the canine population (e.g. a specific breed).
丹麦兽医癌症登记处（DVCR）成立于 2005 年 5 月，旨在收集丹麦犬猫群体中肿瘤的信息。来自丹麦 60 多家诊所的从业者已经提交了这些物种的数据。本研究的目的是特别关注肥大细胞瘤（MCT），根据向 DVCR 报告的信息，调查犬皮肤肿瘤的发生、性别分布、生物学行为、位置、类型、使用的诊断方法和治疗方法。
2005 年 5 月 15 日至 2008 年 2 月 29 日，共提交了 1768 例犬皮肤、皮下或附属物肿瘤的病例报告。其中，765 例（43%）通过细胞学或组织病理学证实。
大多数犬患有良性肿瘤（66%），21%为恶性肿瘤。最常见的恶性肿瘤是 MCT 和软组织肉瘤，而良性肿瘤中最常见的是脂肪瘤和组织细胞瘤。肿瘤的位置主要在真皮、皮下或肛周区域。丹麦犬皮肤肿瘤的发生、性别分布、生物学行为和位置与早期报告相似，但也存在一些国家差异。观察到 MCT 的分级与手术治疗病例的比例之间存在相关性。
像 DVCR 这样的基于人群的癌症登记处对于收集关于肿瘤发生和分布的非选择性原始信息非常重要。DVCR 提供了有关犬皮肤肿瘤病例的详细信息，并可以作为研究肿瘤疾病亚组（例如 MCT）或犬群亚组（例如特定品种）的平台。
