Endocrine Research Unit, Mayo Clinic, Rochester, MN 55902, USA.
Diabetes Res Clin Pract. 2010 Apr;88(1):117-24. doi: 10.1016/j.diabres.2009.12.025. Epub 2010 Jan 21.
Comparing waist circumference (WC) role in diabetes risk prediction and diagnosis of metabolic syndrome (MS) in different populations.
Population-based samples from Australia (n=9026) and Iran (n=8259) were studied in 2000 and followed for approximately 4 years. Follow-up attendance was approximately 58% and mean age was 51 vs. 47. Pearson correlations calculated between WC and other MS components. ROC for the role of WC in the prediction of incident diabetes was used.
Prevalences of MS (48% vs. 28%), an increased WC (58.5% vs. 54.5%), low HDL-C (35% vs. 11.2%), high triglyceride (52.2% vs. 29.6%) were significantly higher in Iran. Fasting glucose >or=5.6mmol/L was higher in Australia (26% vs. 23%). Hypertension was no different ( approximately 38%). Pearson correlations between WC and other MS components were stronger in Australians: FPG (0.32 vs. 0.2), HDL (0.47 vs. 0.16), TG (0.38 vs. 0.30) and SBP (0.38 vs. 0.36). Among women, area under ROC curve for WC as a predictor for diabetes was significantly higher for Australians (0.76 vs. 0.68, p<0.001) with no difference among men (0.69 vs. 0.71, p=0.4).
WC was more strongly related to other components of MS in Australia. Association between WC and MS or incident diabetes varies between ethnicities.
比较腰围（WC）在不同人群中预测糖尿病风险和代谢综合征（MS）诊断中的作用。
本研究对 2000 年澳大利亚（n=9026）和伊朗（n=8259）的人群进行了基于人群的抽样研究，并进行了大约 4 年的随访。随访出勤率约为 58%，平均年龄为 51 岁 vs. 47 岁。计算了 WC 与其他 MS 成分之间的 Pearson 相关系数。使用 WC 在预测新发糖尿病中的作用的 ROC 曲线。
伊朗的 MS 患病率（48% vs. 28%）、腰围增加（58.5% vs. 54.5%）、低 HDL-C（35% vs. 11.2%）、高甘油三酯（52.2% vs. 29.6%）显著更高。澳大利亚的空腹血糖>或=5.6mmol/L 更高（26% vs. 23%）。高血压无差异（约 38%）。澳大利亚人 WC 与其他 MS 成分之间的 Pearson 相关性更强：FPG（0.32 vs. 0.2）、HDL（0.47 vs. 0.16）、TG（0.38 vs. 0.30）和 SBP（0.38 vs. 0.36）。在女性中，WC 作为糖尿病预测因子的 ROC 曲线下面积在澳大利亚人显著更高（0.76 vs. 0.68，p<0.001），而在男性中无差异（0.69 vs. 0.71，p=0.4）。
WC 与澳大利亚的其他 MS 成分的相关性更强。WC 与 MS 或新发糖尿病之间的关联在不同种族之间存在差异。
