University of California, San Francisco, 401 Parnassus Ave., TRC Box 0984, San Francisco, CA 94143, United States.
Drug Alcohol Depend. 2010 Jun 1;109(1-3):114-9. doi: 10.1016/j.drugalcdep.2009.12.021. Epub 2010 Jan 21.
To evaluate potential mediators of an extended cognitive behavioral smoking cessation intervention.
Analysis of data from a randomized clinical trial of smoking cessation.
The Habit Abatement Clinic, University of California, San Francisco.
Participants were older cigarette smokers (>/=50 years old). Those receiving Standard Treatment (N=100) were compared to those receiving extended cognitive behavioral treatment (N=99).
Negative affect was measured with the Profile of Mood States (POMS), the Medical Outcome Studies 36-item Short-Form Health Survey (SF-36), and the Perceived Stress Scale (PSS). Abstinence-specific social support was measured with the Partner Interaction Questionnaire (PIQ). Motivation to quit and abstinence self-efficacy were measured on 1-10 scales with the Thoughts about Abstinence Questionnaire. All were measured at the beginning of treatment and week 52.
Analyses revealed that extended CBT increased abstinence self-efficacy over the first 52 weeks postcessation. This effect, in turn, was positively associated with 7-day point prevalence abstinence at week 64 while controlling for treatment condition, and eliminated the independent effect of treatment condition on abstinence. The test of mediation indicated a significant effect, and abstinence self-efficacy accounted for 61% to 83% of the total effect of treatment condition on smoking abstinence. Results failed to support a mediational role of negative affect, abstinence-specific social support, or motivation to quit.
The results of the present study are consistent with theories of relapse and studies of more time-limited interventions, and underscore the importance of abstinence self-efficacy in achieving long-term abstinence from cigarettes.
评估延长认知行为戒烟干预的潜在中介因素。
对戒烟的随机临床试验数据进行分析。
加利福尼亚大学旧金山分校的习惯戒除诊所。
参与者为年长的吸烟者(>=50 岁)。接受标准治疗(N=100)的患者与接受延长认知行为治疗(N=99)的患者进行比较。
使用心境状态问卷(POMS)、医疗结局研究 36 项简明健康调查(SF-36)和感知压力量表(PSS)测量负性情绪。使用伴侣互动问卷(PIQ)测量与戒烟相关的社会支持。使用戒烟思考问卷(Thoughts about Abstinence Questionnaire)在 1-10 分的量表上测量戒烟动机和戒烟自我效能。所有测量均在治疗开始时和第 52 周进行。
分析显示,延长认知行为治疗在戒烟后第 52 周内增加了戒烟自我效能。这种效应继而与第 64 周时 7 天点患病率的戒烟率呈正相关,同时控制了治疗条件,消除了治疗条件对戒烟的独立影响。中介检验表明存在显著效应,而戒烟自我效能占治疗条件对吸烟戒断的总效应的 61%至 83%。结果未能支持负性情绪、与戒烟相关的社会支持或戒烟动机的中介作用。
本研究结果与复发理论和更限时干预研究一致,强调了戒烟自我效能在实现长期戒烟方面的重要性。