雌激素受体α和雌激素受体β对行为调节的作用。
Contributions of estrogen receptor-α and estrogen receptor-ß to the regulation of behavior.
作者信息
Tetel Marc J, Pfaff Donald W
机构信息
Neuroscience Program, Wellesley College, Wellesley, MA, USA.
出版信息
Biochim Biophys Acta. 2010 Oct;1800(10):1084-9. doi: 10.1016/j.bbagen.2010.01.008. Epub 2010 Jan 25.
Abstract
Studies of the mechanisms by which estrogens influence brain function and behavior have advanced from the explication of individual hormone receptors, neural circuitry and individual gene expression. Now, we can report patterns of estrogen receptor subtype contributions to patterns of behavior. Moreover, new work demonstrates important contributions of nuclear receptor coactivator expression in the central nervous system. In this paper, our current state of knowledge is reviewed.
摘要
关于雌激素影响大脑功能和行为机制的研究，已经从对单个激素受体、神经回路和单个基因表达的阐释向前迈进。现在，我们能够报告雌激素受体亚型对行为模式的贡献模式。此外，新的研究表明核受体共激活因子在中枢神经系统中的表达具有重要作用。在本文中，我们对当前的知识状况进行了综述。
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