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尼日利亚扎里亚儿童原发性骨肿瘤及肿瘤样病变

Primary bone tumours and tumour-like lesions in children in Zaria, Nigeria.

作者信息

Mohammed Abdullahi, Sani Malami A, Hezekiah Isah A, Enoch Afolayan A O

机构信息

Department of Pathology, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria.

出版信息

Afr J Paediatr Surg. 2010 Jan-Apr;7(1):16-8. doi: 10.4103/0189-6725.59353.

Abstract

BACKGROUND

Studies on bone neoplasms are generally scanty globally and more so in children. Primary bone tumours and tumour-like lesions in children have not been reported from Zaria.

OBJECTIVE

To determine the relative frequencies, sex and age distributions, and anatomical sites of occurrence of primary bone tumours and tumour-like lesions in children in Zaria.

MATERIALS AND METHODS

A retrospective review of histopathology reports of 40 children with bone tumours and tumour-like lesions in 11 years of age.

RESULTS

Benign tumours accounted for 12 (30%) of the 40 tumours reviewed (osteoma 2.5%, osterochondroma 22.5%, fibroma 5%); while malignant tumours occurred in 19 (47.5%) (osteosarcoma 5%, Burkitt's lymphoma 37.5%, diffuse lympholastic lymphoma 5%). Tumour-like lesions accounted for 9 (22.5%), all fibrous dysplasia. Out of 40 tumours, 23 (57.5%) occurred in males and 17 (422.5%) in females. The majority of tumours, 45% occurred in the age group of 10-15 years, followed by 15 (37.5) occurring in the 5-9 years age range. The most common malignany was Burkitt's lymphoma 15 (37.5%). Maxilla was the most common site for malignant (30%) and benign tumours (12.5%).

CONCLUSION

This study has shown that, primary bone tumours are relatively uncommon in children in our setting.

摘要

背景

全球范围内关于骨肿瘤的研究普遍较少,儿童骨肿瘤的研究更是如此。扎里亚尚未有儿童原发性骨肿瘤及肿瘤样病变的报道。

目的

确定扎里亚儿童原发性骨肿瘤及肿瘤样病变的相对频率、性别和年龄分布以及发生的解剖部位。

材料与方法

对11岁以下40例患有骨肿瘤及肿瘤样病变儿童的组织病理学报告进行回顾性分析。

结果

在40例经审查的肿瘤中,良性肿瘤占12例(30%)(骨瘤2.5%,骨软骨瘤22.5%,纤维瘤5%);恶性肿瘤19例(47.5%)(骨肉瘤5%,伯基特淋巴瘤37.5%,弥漫性淋巴细胞淋巴瘤5%)。肿瘤样病变9例(22.5%),均为纤维发育不良。40例肿瘤中,23例(57.5%)发生于男性,17例(42.5%)发生于女性。大多数肿瘤(45%)发生在10 - 15岁年龄组,其次是15例(37.5%)发生在5 - 9岁年龄组。最常见的恶性肿瘤是伯基特淋巴瘤15例(37.5%)。上颌骨是恶性肿瘤(30%)和良性肿瘤(12.5%)最常见的部位。

结论

本研究表明,在我们的研究环境中,原发性骨肿瘤在儿童中相对不常见。

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