Mohammed Abdullahi, Sani Malami A, Hezekiah Isah A, Enoch Afolayan A O
Department of Pathology, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria.
Afr J Paediatr Surg. 2010 Jan-Apr;7(1):16-8. doi: 10.4103/0189-6725.59353.
Studies on bone neoplasms are generally scanty globally and more so in children. Primary bone tumours and tumour-like lesions in children have not been reported from Zaria.
To determine the relative frequencies, sex and age distributions, and anatomical sites of occurrence of primary bone tumours and tumour-like lesions in children in Zaria.
A retrospective review of histopathology reports of 40 children with bone tumours and tumour-like lesions in 11 years of age.
Benign tumours accounted for 12 (30%) of the 40 tumours reviewed (osteoma 2.5%, osterochondroma 22.5%, fibroma 5%); while malignant tumours occurred in 19 (47.5%) (osteosarcoma 5%, Burkitt's lymphoma 37.5%, diffuse lympholastic lymphoma 5%). Tumour-like lesions accounted for 9 (22.5%), all fibrous dysplasia. Out of 40 tumours, 23 (57.5%) occurred in males and 17 (422.5%) in females. The majority of tumours, 45% occurred in the age group of 10-15 years, followed by 15 (37.5) occurring in the 5-9 years age range. The most common malignany was Burkitt's lymphoma 15 (37.5%). Maxilla was the most common site for malignant (30%) and benign tumours (12.5%).
This study has shown that, primary bone tumours are relatively uncommon in children in our setting.
全球范围内关于骨肿瘤的研究普遍较少,儿童骨肿瘤的研究更是如此。扎里亚尚未有儿童原发性骨肿瘤及肿瘤样病变的报道。
确定扎里亚儿童原发性骨肿瘤及肿瘤样病变的相对频率、性别和年龄分布以及发生的解剖部位。
对11岁以下40例患有骨肿瘤及肿瘤样病变儿童的组织病理学报告进行回顾性分析。
在40例经审查的肿瘤中,良性肿瘤占12例(30%)(骨瘤2.5%,骨软骨瘤22.5%,纤维瘤5%);恶性肿瘤19例(47.5%)(骨肉瘤5%,伯基特淋巴瘤37.5%,弥漫性淋巴细胞淋巴瘤5%)。肿瘤样病变9例(22.5%),均为纤维发育不良。40例肿瘤中,23例(57.5%)发生于男性,17例(42.5%)发生于女性。大多数肿瘤(45%)发生在10 - 15岁年龄组,其次是15例(37.5%)发生在5 - 9岁年龄组。最常见的恶性肿瘤是伯基特淋巴瘤15例(37.5%)。上颌骨是恶性肿瘤(30%)和良性肿瘤(12.5%)最常见的部位。
本研究表明,在我们的研究环境中,原发性骨肿瘤在儿童中相对不常见。