Kalia Rachna, Magsalin Rhanda M, Khan Ahsan Y, Kahn David A
Department of Psychiatry, Columbia University College of Physicians and Surgeons, USA.
J Psychiatr Pract. 2010 Jan;16(1):58-62. doi: 10.1097/01.pra.0000367780.18883.d8.
A case is presented of the occurrence of an episode of mania apparently induced by desvenlafaxine, in a patient with a history of major depressive disorder and no apparent history of previous mania or hypo-mania. To our knowledge, this is the first such documented case with this new antidepressant. The discussion focuses on the concept of the bipolar spectrum, and how to view patients who have only become manic while taking antidepressants.
本文报告了一例明显由去甲文拉法辛诱发躁狂发作的病例，该患者有重度抑郁症病史，既往无明显的躁狂或轻躁狂病史。据我们所知，这是使用这种新型抗抑郁药出现此类情况的首例有记录病例。讨论集中在双相谱系的概念，以及如何看待那些仅在服用抗抑郁药时出现躁狂的患者。
