Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong.
Cornea. 2010 Mar;29(3):362-4. doi: 10.1097/ICO.0b013e3181ae2594.
The purpose of this study was to report on Tsukamurella as a mimic of atypical mycobacterial infection.
We report a patient who had received repeated corneal grafts with culture-proven Tsukamurella keratitis.
A slow-progressing corneal abscess that initially developed adjacent to a corneal stitch responded poorly to empiric antibiotic treatment. A preliminary culture report revealed fast-growing mycobacterial species. Treatment adjustments successfully controlled the disease. A final diagnosis of Tsukamurella was subsequently made on the basis of cultures.
Tsukamurella exhibits laboratory similarities to mycobacteria and should be considered in the differential of atypical infection of the ocular surface.
本研究旨在报告土曲霉是一种类似非典型分枝杆菌感染的微生物。
我们报告了一例患者,该患者曾多次接受角膜移植,并经培养证实患有土曲霉角膜炎。
起初位于角膜缝线旁的进展缓慢的角膜脓肿对经验性抗生素治疗反应不佳。初步培养报告显示为快速生长的分枝杆菌。治疗调整成功控制了疾病。最终根据培养结果诊断为土曲霉。
土曲霉在实验室表现与分枝杆菌相似,应在考虑眼表非典型感染的鉴别诊断时考虑到它。