与穿透性角膜移植术相关的非典型分枝杆菌角膜炎：局部应用加替沙星 0.3%治疗成功的病例报告。
Atypical mycobacterium keratitis associated with penetrating keratoplasty: case report of successful therapy with topical gatifloxacin 0.3%.
机构信息
Cornea & Refractive Service, Asociación para Evitar la Ceguera en México, Hospital Dr. Luis Sánchez Bulnes, Vicente Garcia Torres, 46 San Lucas Coyoacan, Mexico City, Mexico.
出版信息
Cornea. 2010 Apr;29(4):468-70. doi: 10.1097/ICO.0b013e3181b532c7.
PURPOSE
To report successful therapy with gatifloxacin 0.3% ophthalmic solution (Zymar) in a patient with atypical mycobacterium keratitis after penetrating keratoplasty.
METHODS
A 58-year-old patient was referred for evaluation of microbial keratitis after penetrating keratoplasty.
RESULTS
Clinical examination of the patient revealed an infiltrate at the inferior graft-host junction with a satellite lesion with a mild inflammatory reaction in the anterior chamber. Microbiologic evaluation confirmed the diagnosis of atypical mycobacteria keratitis. The corneal abscess was completely eradicated with a topical course of gatifloxacin 0.3% with preservation of graft clarity and good visual acuity. Topical treatment with gatifloxacin 0.3% was continued for an additional period of 5 months.
CONCLUSION
Topical gatifloxacin 0.3% may be successfully used to treat microbial keratitis resulting from atypical mycobacteria.
目的
报告一例穿透性角膜移植术后非典型分枝杆菌角膜炎患者经加替沙星 0.3%眼用溶液（泽马可）治疗成功的病例。
方法
一位 58 岁患者因穿透性角膜移植术后微生物性角膜炎而被转诊。
结果
患者的临床检查显示，在移植物与宿主交界处的下部有一个浸润病灶，前房内有一个卫星病灶伴轻度炎症反应。微生物学评估证实了非典型分枝杆菌角膜炎的诊断。局部应用加替沙星 0.3%溶液后，角膜脓肿完全清除，移植物透明，视力良好。继续局部应用加替沙星 0.3%溶液治疗 5 个月。
结论
局部应用加替沙星 0.3%溶液可能成功地用于治疗由非典型分枝杆菌引起的微生物性角膜炎。
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