García Patricia C, Valenzuela Natalia S, Rodríguez M Victoria L, León Eugenia C, Fernández Heríberto J
Escuela de Medicina, Departamento de Laboratorios Clínicos, Pontificia Universidad Católica de Chile, Santiago, Chile.
Rev Chilena Infectol. 2009 Dec;26(6):511-4. Epub 2009 Dec 21.
Campylobacter jejuni is a common agent of enterocolitis in humans. Campylobacteriosis has been recognized as a zoonotic disease whose reservoir is the intestinal flora of poultry. The reposition of fluid and electrolytes is the recommended treatment, and antimicrobials are required only in severe and/or in prolonged disease. Given the emergence of resistance to drugs commonly used in the treatment of acute diarrhea, we studied the antimicrobial susceptibility of 73 strains of Campylobacter jejuni isolated from stool culture. The antimicrobials tested were: erythromycin, azithromycin, ampicillin and ciprofloxacin. Of the 73 strains tested by E-test, 32.4% were resistant to ciprofloxacin and 6.4% were resistant to ampicillin. Resistance to erythromycin and azithromycin was not detected. The surveillance of antimicrobial resistance of Campylobacter jejuni is important in the evaluation of empirically used antimicrobials in the treatment of bacterial enterocolitis.
空肠弯曲菌是人类小肠结肠炎的常见病原体。弯曲菌病已被确认为一种人畜共患病,其宿主为家禽的肠道菌群。补充液体和电解质是推荐的治疗方法,仅在严重和/或病程延长的疾病中需要使用抗菌药物。鉴于治疗急性腹泻常用药物出现耐药性,我们研究了从粪便培养物中分离出的73株空肠弯曲菌的抗菌药敏性。所测试的抗菌药物有:红霉素、阿奇霉素、氨苄西林和环丙沙星。通过E试验检测的73株菌株中,32.4%对环丙沙星耐药,6.4%对氨苄西林耐药。未检测到对红霉素和阿奇霉素的耐药性。监测空肠弯曲菌的抗菌耐药性对于评估治疗细菌性小肠结肠炎时经验性使用的抗菌药物很重要。