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[西班牙卡斯特利翁02卫生区沙门氏菌血清型、噬菌体型及抗生素耐药性的演变(2000 - 2006年)]

[Evolution of serotypes, phagotypes and antibiotic resistance of Salmonella spp in the 02 health district of Castellón, Spain (2000-2006)].

作者信息

Tirado Ma Dolores B, Moreno Rosario M, Celades Ma Elena P, Bellido-Blasco Juan, Pardo Francisco J S

机构信息

Hospital General de Castellón, Sección Microbiología, Castellón, España.

出版信息

Rev Chilena Infectol. 2009 Dec;26(6):520-7. Epub 2009 Dec 21.

Abstract

Retrospective study of serotypes, phage types and antibiotic resistance of Salmonella spp isolates in the 02 Health District of Castellón, Spain (2000-2006). Strains were serotyped using commercial sera, and they were tested for antimicrobial susceptibility with automated systems. Serotyping confirmation and phage typing were performed by the National Reference Laboratory. A total of 1505 strains were isolated, with 49 different serotypes, being the most frequent Enteritidis. The most common serotype/phage type combination was S. Enteritidis phagetype 1. Of the isolates 81.6% were susceptible to amoxicillin/clavulanic acid; 65.2% to ampicillin; 99.9% to ciprofloxacin; 93.4% to trimethoprim-sulphametoxazole; and 99.8% to cefotaxime. Molecular methods could be useful to complete epidemiologic studies since 25% of our isolates showed the same serotype/phage type combination. In our health district antimicrobial resistance in Salmonella is not an important problem.

摘要

西班牙卡斯特利翁02卫生区沙门氏菌分离株血清型、噬菌体类型及抗生素耐药性的回顾性研究(2000 - 2006年)。使用商用血清对菌株进行血清分型,并通过自动化系统检测其对抗菌药物的敏感性。血清型确认和噬菌体分型由国家参考实验室进行。共分离出1505株菌株,有49种不同血清型,其中肠炎沙门氏菌最为常见。最常见的血清型/噬菌体类型组合是肠炎沙门氏菌噬菌体类型1。在分离株中,81.6%对阿莫西林/克拉维酸敏感;65.2%对氨苄西林敏感;99.9%对环丙沙星敏感;93.4%对甲氧苄啶-磺胺甲恶唑敏感;99.8%对头孢噻肟敏感。由于25%的分离株显示相同的血清型/噬菌体类型组合,分子方法可能有助于完善流行病学研究。在我们的卫生区,沙门氏菌的抗生素耐药性不是一个重要问题。

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