Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China.
Foodborne Pathog Dis. 2011 Aug;8(8):921-7. doi: 10.1089/fpd.2010.0827. Epub 2011 Apr 14.
Foodborne infections are an important public health problem in China. In 2008, we conducted surveillance for laboratory-confirmed nontyphoidal Salmonella to monitor trends for this infection in China and to build capacity for rapid detection and response to foodborne outbreaks. Salmonella isolates from patients with diarrhea were sent from hospitals to local public health laboratories for confirmation, serotyping, and antimicrobial susceptibility testing. A total of 126 hospitals in 44 cities and counties from 8 provinces provided isolates and epidemiologic data for analysis. Of 23,140 stool specimens submitted to clinical laboratories, 662 (3%) grew Salmonella enterica. Salmonella were most commonly detected between April and October. The median age of infected patients was 27 years; 34% of infections occurred in patients <5 years old. Of the 662 isolates, we found 73 serotypes, of which serotype Enteritidis (31%) and serotype Typhimurium (26%) were the most common. The prevalence of resistance was high for clinically important antimicrobial agents, including ampicillin (41%) and ciprofloxacin (6%). More than 60% of isolates, including 35% of all Typhimurium, were resistant to three or more antimicrobial agents. In this first multiprovince surveillance report of laboratory-confirmed Salmonella infections in China, we found that Enteritidis and Typhimurium are the most common serotypes and that efforts to reduce antimicrobial resistance among Salmonella in China are needed. Although no outbreaks were detected using this system, efforts to improve this system's capacity to do so are underway.
食源性感染在中国是一个重要的公共卫生问题。2008 年，我们开展了对实验室确诊的非伤寒沙门氏菌的监测，以监测中国此类感染的趋势，并建立对食源性暴发的快速检测和应对能力。从腹泻患者身上分离出的沙门氏菌菌株从医院送到当地公共卫生实验室进行确认、血清分型和抗菌药物敏感性测试。来自 8 个省的 44 个城市和县城的 126 家医院提供了分离株和流行病学数据进行分析。在提交给临床实验室的 23140 份粪便标本中，有 662 份（3%）生长出肠沙门氏菌。沙门氏菌最常于 4 月至 10 月间检出。受感染患者的中位年龄为 27 岁；34%的感染发生在<5 岁的患者中。在 662 株分离株中，我们发现了 73 种血清型，其中肠炎沙门氏菌（31%）和鼠伤寒沙门氏菌（26%）最为常见。对包括氨苄西林（41%）和环丙沙星（6%）在内的重要抗菌药物的耐药率很高。超过 60%的分离株，包括所有鼠伤寒沙门氏菌的 35%，对三种或更多种抗菌药物耐药。在这第一篇中国实验室确诊沙门氏菌感染的多省份监测报告中，我们发现肠炎沙门氏菌和鼠伤寒沙门氏菌是最常见的血清型，需要在中国减少沙门氏菌的抗菌药物耐药性。虽然使用该系统未检测到暴发，但正在努力提高该系统的检测能力。
