Luedders D W, Hornemann A, Fritzsching B, Thill M, Beyer D A, Diedrich K, Bohlmann M K
Klinik für Frauenheilkunde und Geburtshilfe, Universitätsklinikum Schleswig-Holstein - Campus Lübeck, Lübeck, Germany.
Z Geburtshilfe Neonatol. 2009 Dec;213(6):228-33. doi: 10.1055/s-0029-1241846. Epub 2010 Jan 22.
Twin pregnancies and gestations after assisted reproductive therapy (ART) are of special obstetric significance with regard to their associated risks. However, little is known about preventive approaches specifically evaluated for these constellations.
A selective literature search was conducted to examine possible preventive approaches for complications such as hypertensive disorders, anaemia, gestational diabetes, prematurity, and others, seen significantly more often in twin gestations and pregnancies after ART.
For both constellations, preventive approaches are not specifically evaluated for the majority of complications. For some preventive methods a possible detrimental effect cannot even be ruled out.
The knowledge about specific preventive approaches against complications in twin pregnancies and gestations after ART is scarce. More prospective trials are urgently needed to assess the risks and benefits of prophylactic approaches for these risk constellations.
双胎妊娠以及辅助生殖治疗（ART）后的妊娠因其相关风险而具有特殊的产科意义。然而，对于专门针对这些情况评估的预防方法知之甚少。
进行了一项选择性文献检索，以研究针对双胎妊娠和ART后妊娠中更常见的并发症（如高血压疾病、贫血、妊娠期糖尿病、早产等）的可能预防方法。
对于这两种情况，大多数并发症的预防方法都未得到专门评估。对于一些预防方法，甚至不能排除可能的有害影响。
关于双胎妊娠和ART后妊娠并发症的特定预防方法的知识匮乏。迫切需要更多前瞻性试验来评估这些风险情况的预防方法的风险和益处。
