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主动脉瓣心内膜炎中的感染性冠状动脉栓塞

Septic coronary embolism in aortic valvular endocarditis.

作者信息

Kessavane Anitha, Marticho Paul, Zogheib Elie, Lorne Emmanuel, Dupont Hervé, Tribouilloy Christophe, Remadi Jean Paul

机构信息

Department of Anesthesiology, South Hospital, Laennec avenue 80054, Amiens, Salouel, France.

出版信息

J Heart Valve Dis. 2009 Sep;18(5):572-4.

Abstract

Acute myocardial infarction due to septic coronary emboli in active infective endocarditis is rare, but may be fatal. The case is reported of a 58-year-old man who presented with wrist arthritis, which resulted in acute aortic valvular endocarditis. Echocardiography revealed 3 mm vegetations on the posterior and anterior valve cusps, and aortic regurgitation (grade 3-4). As the patient's clinical status was stable, medical treatment was selected which included antibiotic therapy, but after four weeks the patient reported an acute anterior chest pain. Coronary angiography revealed stenosis of the left anterior descending (LAD) artery, due to septic embolism. The patient was referred for emergency cardiac surgery, at which a surgical thrombectomy and coronary artery bypass grafting with reconstruction of the LAD artery were performed, along with aortic valve replacement using a bioprosthesis. The postoperative course was uneventful and the patient was discharged on postoperative day 15. An adapted oral antibiotherapy was continued for a further six-week period.

摘要

活动性感染性心内膜炎所致的脓毒性冠状动脉栓塞引起的急性心肌梗死较为罕见,但可能致命。本文报道了一名58岁男性患者,最初表现为腕关节炎,进而发展为急性主动脉瓣心内膜炎。超声心动图显示主动脉瓣前后叶瓣尖有3毫米的赘生物,伴有主动脉瓣反流(3 - 4级)。由于患者临床状况稳定,选择了包括抗生素治疗在内的内科治疗,但四周后患者出现急性前胸疼痛。冠状动脉造影显示左前降支(LAD)动脉因脓毒性栓塞而狭窄。患者被转诊接受急诊心脏手术,术中进行了手术取栓、LAD动脉重建的冠状动脉旁路移植术,同时使用生物假体进行主动脉瓣置换。术后过程顺利,患者于术后第15天出院。继续调整口服抗生素治疗,持续六周。

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