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西印度群岛六例上颌成釉细胞瘤病例回顾:再次冷冻手术作为预防性手术干预措施

Review of six cases of maxillary ameloblastoma from the West Indies: re-entry cryosurgery as prophylactic surgical intervention.

作者信息

Ogunsalu C, Scipio E, Williams N

机构信息

Oral Disease Unit, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad amd Tobago.

出版信息

West Indian Med J. 2009 Sep;58(4):398-403.

PMID:20099786
Abstract

Maxillary ameloblastoma is a rare histopathological entity. A total of six cases of histologically confirmed maxillary ameloblastoma from the West Indies is reviewed. Three of the cases were taken from a total of 47 histologically confirmed ameloblastoma over a 15-year period (1980-1995) from two major maxillofacial units in Jamaica. Two other cases were from documentation in Jamaica between 2000 and 2002, one of which occurred in a 13-year-old girl (these two patients have been followed-up periodically to 2006). The sixth case was from the records of the maxillofacial department of the University of the West Indies in Trinidad and Tobago. This last patient, at a recent review, has inoperable recurrence. These cases were reviewed with respect to demographics (patient's age and gender), location and extent of tumour, radiological features, concurrent involvement of the mandible, treatment with special emphasis on current treatment modality and follow-up. The findings do not differ from what has been documented by other authors from other parts of the world. Because of the radiographic anatomy of the maxilla, recurrence may be detected late despite such occurring earlier following initial surgical management. It is for this reason that we suggest re-entry cryosurgery for prevention of recurrence for maxillary ameloblastoma. The only case of maxillary ameloblastoma that had re-entry cryosurgery continues to benefit from absence of recurrence at periodic follow-ups at four years post-primary surgical management (which was enucleation).

摘要

上颌成釉细胞瘤是一种罕见的组织病理学实体。本文回顾了西印度群岛6例经组织学确诊的上颌成釉细胞瘤病例。其中3例取自牙买加两个主要颌面科室1980年至1995年15年间共47例经组织学确诊的成釉细胞瘤。另外2例来自牙买加2000年至2002年的记录,其中1例发生在一名13岁女孩身上(这两名患者定期随访至2006年)。第6例来自特立尼达和多巴哥西印度群岛大学颌面外科的记录。在最近一次复查时,最后这名患者出现了无法手术切除的复发。对这些病例进行了人口统计学(患者年龄和性别)、肿瘤位置和范围、放射学特征、下颌骨是否同时受累、治疗(特别强调当前治疗方式)及随访等方面的回顾。研究结果与世界其他地区其他作者所记录的情况并无差异。由于上颌骨的放射解剖结构,尽管复发在初次手术治疗后较早发生,但可能较晚才被发现。正是出于这个原因,我们建议采用再次手术冷冻治疗来预防上颌成釉细胞瘤的复发。唯一接受再次手术冷冻治疗的上颌成釉细胞瘤病例在初次手术治疗(摘除术)后四年的定期随访中持续受益于无复发情况。

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Review of six cases of maxillary ameloblastoma from the West Indies: re-entry cryosurgery as prophylactic surgical intervention.西印度群岛六例上颌成釉细胞瘤病例回顾:再次冷冻手术作为预防性手术干预措施
West Indian Med J. 2009 Sep;58(4):398-403.
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