Centre de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut d'Investigació Sanitària Pere Virgili, Reus, Catalunya, Spain.
Fertil Steril. 2010 Aug;94(3):1132-4. doi: 10.1016/j.fertnstert.2009.11.043. Epub 2010 Jan 25.
In this observational, case-control study in infertile women, we observed elevated serum oxidative stress that was significantly correlated with an increase in serum paraoxonase-1 activity and without any evidence of a proinflammatory reaction. These results suggest a protective role of paraoxonase-1 against inflammation in this clinical setting.
在这项针对不孕女性的观察性病例对照研究中,我们观察到血清氧化应激水平升高,且与血清对氧磷酶-1 活性的升高显著相关,而没有任何炎症反应的证据。这些结果表明,在这种临床情况下,对氧磷酶-1 对炎症具有保护作用。