Batty G David, Deary Ian J, Benzeval Michaela, Der Geoff
MRC Social and Public Health Sciences Unit, University of Glasgow, Glasgow, UK.
Eur J Cardiovasc Prev Rehabil. 2010 Feb;17(1):24-7. doi: 10.1097/HJR.0b013e328321311b.
To compare the strength of the association between intelligence quotient (IQ) and cardiovascular disease (CVD) mortality with the predictive power for established risk factors.
Population-based cohort study of 1145 men and women with IQ test scores, a range of established risk factors, and 20-year mortality surveillance.
When CVD mortality was the outcome of interest, the relative index of inequality (sex-adjusted hazard ratio, 95% confidence interval) for the most disadvantaged relative to the advantaged persons was (in descending order of magnitude for the top five risk factors): 5.58 (2.89, 10.8) for cigarette smoking; 3.76 (2.14, 6.61) for IQ; 3.20 (1.85, 5.54) for income; 2.61 (1.49, 4.57) for systolic blood pressure and 2.06 (1.07, 3.99) for physical activity. Mutual adjustment led to some attenuation of these relationships. Similar observations were made in the analyses featuring all deaths where, again, IQ was the second most powerful predictor of mortality risk.
In this cohort, lower intelligence scores were associated with increased rates of CVD and total mortality at a level of magnitude greater than most established risk factors.
比较智商（IQ）与心血管疾病（CVD）死亡率之间的关联强度以及与既定风险因素的预测能力。
基于人群的队列研究，研究对象为1145名有智商测试分数、一系列既定风险因素且接受了20年死亡率监测的男性和女性。
当心血管疾病死亡率为感兴趣的结局时，最弱势人群相对于优势人群的不平等相对指数（性别调整风险比，95%置信区间）（按前五项风险因素的大小降序排列）：吸烟为5.58（2.89，10.8）；智商为3.76（2.14，6.61）；收入为3.20（1.85，5.54）；收缩压为2.61（1.49，4.57）；身体活动为2.06（1.07，3.99）。相互调整导致这些关系有所减弱。在所有死亡情况的分析中也有类似观察结果，同样，智商是死亡风险的第二大预测因素。
在这个队列中，较低的智商分数与心血管疾病和总死亡率的增加相关，其关联程度大于大多数既定风险因素。
