1型糖尿病患者自体骨髓血自体移植后胰岛素分泌的再生 - Suppr

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超能文献

Regeneration of insulin production by autologous bone marrow blood autotransplantation in patients with type 1 diabetes.

作者信息

Esmatjes E, Montaña X, Real M I, Blanco J, Conget I, Casamitjana R, Rovira M, Gomis R, Marin P

机构信息

Diabetes Unit, Hospital Clinic Universitari, C/Villarroel 170, 08036 Barcelona, Spain.

出版信息

Diabetologia. 2010 Apr;53(4):786-9. doi: 10.1007/s00125-010-1660-9. Epub 2010 Jan 26.

DOI:10.1007/s00125-010-1660-9

PMID:20101385

Abstract

摘要

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Regeneration of insulin production by autologous bone marrow blood autotransplantation in patients with type 1 diabetes.1型糖尿病患者自体骨髓血自体移植后胰岛素分泌的再生

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Umbilical Cord Mesenchymal Stromal Cell With Autologous Bone Marrow Cell Transplantation in Established Type 1 Diabetes: A Pilot Randomized Controlled Open-Label Clinical Study to Assess Safety and Impact on Insulin Secretion.脐带间质基质干细胞联合自体骨髓单个核细胞移植治疗 1 型糖尿病：一项评估安全性和对胰岛素分泌影响的开放性、随机对照临床研究。

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Pancreatic beta cell function in children and adolescents after bone marrow transplantation.骨髓移植后儿童和青少年的胰腺β细胞功能

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Sustained oscillatory insulin secretion after pancreas transplantation.胰腺移植后持续振荡性胰岛素分泌。

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(Re)generating Human Beta Cells: Status, Pitfalls, and Perspectives.(再)生成人胰岛β细胞：现状、陷阱和展望。

Physiol Rev. 2018 Jul 1;98(3):1143-1167. doi: 10.1152/physrev.00034.2016.

Bone marrow-derived stem cell transplantation for the treatment of insulin-dependent diabetes.骨髓源性干细胞移植治疗胰岛素依赖型糖尿病。

Rev Diabet Stud. 2010 Summer;7(2):144-57. doi: 10.1900/RDS.2010.7.144. Epub 2010 Aug 10.

本文引用的文献

Autologous umbilical cord blood transfusion in very young children with type 1 diabetes.自体脐带血输注治疗 1 型糖尿病的非常年幼的儿童。

Diabetes Care. 2009 Nov;32(11):2041-6. doi: 10.2337/dc09-0967.

Efficacy of autologous bone marrow-derived stem cell transplantation in patients with type 2 diabetes mellitus.自体骨髓源性干细胞移植治疗 2 型糖尿病的疗效。

Stem Cells Dev. 2009 Dec;18(10):1407-16. doi: 10.1089/scd.2009.0164.

Differentiation of bone marrow-derived mesenchymal stem cells from diabetic patients into insulin-producing cells in vitro.体外将糖尿病患者骨髓来源的间充质干细胞分化为胰岛素分泌细胞。

Chin Med J (Engl). 2007 May 5;120(9):771-6.

Human bone marrow mesenchymal stem cells can express insulin and key transcription factors of the endocrine pancreas developmental pathway upon genetic and/or microenvironmental manipulation in vitro.在体外进行基因和/或微环境操作后，人骨髓间充质干细胞可表达胰岛素及内分泌胰腺发育途径的关键转录因子。

Stem Cells. 2005 Apr;23(4):594-603. doi: 10.1634/stemcells.2004-0123.

In vivo and in vitro characterization of insulin-producing cells obtained from murine bone marrow.从小鼠骨髓中获取的胰岛素生成细胞的体内和体外特性研究

Diabetes. 2004 Jul;53(7):1721-32. doi: 10.2337/diabetes.53.7.1721.

No evidence for significant transdifferentiation of bone marrow into pancreatic beta-cells in vivo.没有证据表明在体内骨髓会大量转分化为胰腺β细胞。

Diabetes. 2004 Mar;53(3):616-23. doi: 10.2337/diabetes.53.3.616.

In vivo derivation of glucose-competent pancreatic endocrine cells from bone marrow without evidence of cell fusion.从骨髓中体内衍生出具有葡萄糖反应能力的胰腺内分泌细胞，且无细胞融合迹象。

J Clin Invest. 2003 Mar;111(6):843-50. doi: 10.1172/JCI16502.

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