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单纯支架置入术治疗大型和巨大型颅内动脉瘤:局限性和并发症。

Sole stenting of large and giant intracranial aneurysms with self-expanding intracranial stents-limits and complications.

机构信息

Clinical Institute of Diagnostic and Interventional Radiology, University Hospital Center Zagreb, Kispaticeva 12, Zagreb, Croatia.

出版信息

Acta Neurochir (Wien). 2010 May;152(5):763-9. doi: 10.1007/s00701-009-0592-y. Epub 2010 Jan 27.

Abstract

BACKGROUND

Intracranial aneurysms may be difficult for endovascular treatment due to size, fusiform shape, or wide neck. In such patients, intracranial stents are used to support the coils in the aneurysm sac, or they may be used as a sole stenting technique to divert the blood flow without coils. The aim of this paper is to contribute to the existing data by reviewing the risks of sole stenting of large and giant aneurysms.

METHODS

We treated seven patients with nine aneurysms by self-expanding intracranial stents, either by a single or multiple stents in a stent-in-stent configuration. The follow-up was performed by digital subtraction angiography with a mean follow-up time of 6 months.

RESULTS

A positive response to stenting occurred in five out of seven patients (71%) and six out of nine aneurysms (67%). The aneurysms were occluded in two patients, and incomplete results were noted in three patients. The symptoms due to the compression of cranial nerves resolved in four patients (57%). Procedure-related subarachnoid hemorrhage occurred in two out of seven patients (29%), with death of one patient as a result of hemorrhage (14%).

CONCLUSIONS

Sole stenting of large and giant aneurysms with self-expanding intracranial stents may be associated with a higher risk than previously reported. The effect of stenting on intra-aneurysmal flow in such aneurysms, even after the placement of multiple overlapping stents, seems to be unpredictable.

摘要

背景

颅内动脉瘤由于体积较大、梭形或宽颈等原因,可能难以进行血管内治疗。在这些患者中,颅内支架用于支撑动脉瘤囊内的线圈,或者可以作为一种单纯的支架技术,在不放置线圈的情况下改变血流方向。本文旨在通过回顾单纯支架治疗大型和巨大型动脉瘤的风险,为现有数据做出贡献。

方法

我们采用自膨式颅内支架对 7 名患者的 9 个动脉瘤进行了治疗,采用支架内支架技术,单个或多个支架。平均随访 6 个月,通过数字减影血管造影进行随访。

结果

7 名患者中的 5 名(71%)和 9 个动脉瘤中的 6 个(67%)对支架治疗有积极反应。2 名患者的动脉瘤闭塞,3 名患者的结果不完全。4 名患者因颅神经受压引起的症状得到缓解(57%)。7 名患者中有 2 名(29%)发生与手术相关的蛛网膜下腔出血,1 名患者因出血死亡(14%)。

结论

用自膨式颅内支架单纯治疗大型和巨大型动脉瘤的风险可能高于以往报道。即使放置多个重叠支架,支架对这类动脉瘤内血流的影响似乎也难以预测。

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