Department of Mechanical Engineering, Ibaraki University, 4-12-1, Nakanarusawa, Hitachi, Ibaraki, 316-8511, Japan.
J Mater Sci Mater Med. 2010 May;21(5):1641-8. doi: 10.1007/s10856-010-3994-8. Epub 2010 Jan 26.
Fluorinated diamond-like carbon (F-DLC) films were deposited on polytetrafluoroethylene (PTFE) using radio frequency (RF) plasma-enhanced chemical vapor deposition (CVD) by changing the ratio of tetrafluoromethane (CF(4)) and methane (CH(4)). To enhance the adhesion strength of the F-DLC film to the PTFE substrate, the PTFE surface was modified with a N(2) plasma pre-treatment. XPS analysis of the films showed that the C-C bond decreased with increases in the CF(4) ratio, whereas the C-F bond increased with the CF(4) ratio. The F/C ratio of the film also increased with the CF(4) ratio. The pull-out test showed that the adhesion strengths of the films (CF(4)-0-60%) were improved with the plasma pre-treatment. In the film without the plasma pre-treatment, adhesion strength increased with the CF(4) ratio. In contrast, in the case with the plasma pre-treatment, the adhesion strength of the F-DLC film decreased with the increased CF(4) ratio. Regarding the adsorption of albumin, fibrinogen, and gamma-globulin, the amount of adsorbed albumin on the film decreased with an increasing CF(4) ratio, and the amount of adsorbed fibrinogen and gamma-globulin increased with the CF(4) ratio. The CF(4)-0% DLC film showed the most adsorbed albumin and the least adsorbed fibrinogen and gamma-globulin. This indicates that the CF(4)-0% DLC film has higher anti-thrombogenicity than the F-DLC film.
含氟类金刚石碳（F-DLC）薄膜采用射频（RF）等离子体增强化学气相沉积（CVD）技术，通过改变四氟甲烷（CF4）和甲烷（CH4）的比例沉积在聚四氟乙烯（PTFE）上。为了提高 F-DLC 薄膜与 PTFE 基底的黏附强度，采用 N2等离子体预处理对 PTFE 表面进行改性。通过 XPS 分析可知，随着 CF4比例的增加，C-C 键减少，而 C-F 键增加，同时薄膜的 F/C 比也随着 CF4比例的增加而增加。拉脱试验表明，经等离子体预处理后，薄膜（CF4-0-60%）的黏附强度得到提高。在未经等离子体预处理的薄膜中，黏附强度随 CF4比例的增加而增加。相反，在经过等离子体预处理的情况下，F-DLC 薄膜的黏附强度随 CF4比例的增加而降低。在白蛋白、纤维蛋白原和γ-球蛋白的吸附方面，随着 CF4比例的增加，薄膜上吸附的白蛋白量减少，而吸附的纤维蛋白原和γ-球蛋白量增加。CF4-0% DLC 薄膜吸附的白蛋白最多，而吸附的纤维蛋白原和γ-球蛋白最少。这表明 CF4-0% DLC 薄膜的抗血栓形成性能优于 F-DLC 薄膜。
