Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan, 388-1 Pungnap-Dong, Songpa-Gu, Seoul 138-736, South Korea.
World J Gastroenterol. 2010 Jan 28;16(4):490-5. doi: 10.3748/wjg.v16.i4.490.
To assess the indications, findings, therapeutic procedures, safety, and complications of endoscopic retrograde cholangiopancreatography (ERCP) performed in Korean children.
The demographic characteristics, indications for ERCP, findings, therapeutic procedures, and complications of 122 pediatric patients who underwent 245 ERCPs in the Asan Medical Center between June 1994 and March 2008 were investigated.
The mean age of the 122 patients was 8.0 +/- 4.2 years. Indications were biliary pathology in 78 (64.0%), pancreatic pathology in 43 (35.2%), and chronic abdominal pain in one. Biliary indications included choledochal cysts in 40, choledocholithiasis in 24, suspected sclerosing cholangitis in 8, trauma in 2, and other conditions in 4. Pancreatic indications included acute pancreatitis in 7, acute recurrent pancreatitis in 11, chronic pancreatitis in 20, trauma in 3, and pancreatic mass in 2. Of the 245 ERCPs, success rate was 98.4% and 190 (77.6%) were for therapeutic purposes, including endoscopic nasal drainage (51.8%), biliary sphincterotomy (38.0%), pancreatic sphincterotomy (23.3%), stent insertion (15.1%), stone extraction (18.8%), and balloon dilatation (11.0%). Complications were post-ERCP pancreatitis in 16 (6.5%), ileus in 23 (9.4%), hemorrhage in 2 (0.8%), perforation in 2 (0.8%), sepsis in 1 (0.4%), and impacted basket in 1 (0.4%). There were no procedure-related deaths, and most complications improved under supportive care.
This study showed that there is a high incidence of choledochal cyst and diagnostic and therapeutic ERCP for the management of various biliary and pancreatic diseases was safe and effective in Korean children.
评估在韩国儿童中进行的内镜逆行胰胆管造影术(ERCP)的适应证、发现、治疗程序、安全性和并发症。
研究了 1994 年 6 月至 2008 年 3 月期间在 Asan 医疗中心接受 245 次 ERCP 的 122 例儿科患者的人口统计学特征、ERCP 的适应证、发现、治疗程序和并发症。
122 例患者的平均年龄为 8.0±4.2 岁。适应证为胆道病变 78 例(64.0%)、胰腺病变 43 例(35.2%)和慢性腹痛 1 例。胆道适应证包括胆总管囊肿 40 例、胆总管结石 24 例、疑似硬化性胆管炎 8 例、外伤 2 例和其他情况 4 例。胰腺适应证包括急性胰腺炎 7 例、复发性胰腺炎 11 例、慢性胰腺炎 20 例、外伤 3 例和胰腺肿块 2 例。245 次 ERCP 中,成功率为 98.4%,190 次(77.6%)为治疗性目的,包括内镜鼻引流(51.8%)、胆管括约肌切开术(38.0%)、胰腺括约肌切开术(23.3%)、支架置入术(15.1%)、结石取出术(18.8%)和球囊扩张术(11.0%)。并发症包括 ERCP 后胰腺炎 16 例(6.5%)、肠梗阻 23 例(9.4%)、出血 2 例(0.8%)、穿孔 2 例(0.8%)、败血症 1 例(0.4%)和嵌塞篮 1 例(0.4%)。无与操作相关的死亡,大多数并发症在支持治疗下得到改善。
本研究表明,韩国儿童中胆总管囊肿的发病率较高,对各种胆道和胰腺疾病进行诊断和治疗性 ERCP 是安全有效的。