Rogers D G, Frey M L, Hogg A
Veterinary Diagnostic Center, University of Nebraska, Lincoln 68583-0907.
J Am Vet Med Assoc. 1991 Feb 1;198(3):450-2.
A midwestern producer reported high incidence of conjunctivitis and keratoconjunctivitis in a herd of crossbred finishing swine. Complete necropsy was performed on 3 pigs with bilateral mucopurulent conjunctivitis and chemosis; other gross lesions were not seen. Mycoplasma sp was isolated from conjunctival swab specimens obtained from 1 pig; small numbers of streptococci and coagulase-negative staphylococci were isolated from conjunctival swab specimens from all 3 pigs. Neither swine influenza virus nor pseudorabies virus was isolated from conjunctival swab specimens. Histologically, the 3 pigs had chronic lymphoplasmacytic conjunctivitis with lymphofollicular hyperplasia and foci of epithelial and goblet cell hyperplasia. Ultrastructural examination of conjunctival specimens from the 3 pigs revealed large numbers of Mycoplasma-like organisms adhered to superficial conjunctival cells. Mycoplasma-like organisms also were seen in membrane-bound vacuoles in superficial conjunctival cells. Bacteria (including chlamydiae) or viruses were not seen ultrastructurally. The lymphoproliferative nature of the conjunctival lesion and the evidence of adhered and intracellular organisms suggested an etiologic role for a Mycoplasma-like organism in the disease in these pigs.
一位中西部的养殖者报告称,一群杂交育肥猪中结膜炎和角膜结膜炎的发病率很高。对3头患有双侧黏液脓性结膜炎和结膜水肿的猪进行了完整的尸检;未发现其他肉眼可见的病变。从1头猪的结膜拭子标本中分离出支原体属;从所有3头猪的结膜拭子标本中均分离出少量链球菌和凝固酶阴性葡萄球菌。从结膜拭子标本中未分离出猪流感病毒和伪狂犬病病毒。组织学检查显示,这3头猪患有慢性淋巴细胞浆细胞性结膜炎,伴有淋巴滤泡增生以及上皮细胞和杯状细胞增生灶。对这3头猪的结膜标本进行超微结构检查发现,大量支原体样生物附着于结膜表层细胞。在结膜表层细胞的膜结合空泡中也可见到支原体样生物。超微结构检查未发现细菌(包括衣原体)或病毒。结膜病变的淋巴细胞增生性质以及附着和细胞内生物的证据表明,支原体样生物在这些猪的疾病中起病因作用。