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与……相关的猪结膜炎暴发。 (原文不完整,翻译只能到此程度)

Swine conjunctivitis outbreaks associated with .

作者信息

Resende Talita P, Pieters Maria, Vannucci Fabio A

机构信息

Veterinary and Biomedical Sciences (Resende), College of Veterinary Medicine, University of Minnesota, Saint Paul, MN.

Veterinary Population Medicine Department (Pieters), College of Veterinary Medicine, University of Minnesota, Saint Paul, MN.

出版信息

J Vet Diagn Invest. 2019 Sep;31(5):766-769. doi: 10.1177/1040638719865767. Epub 2019 Jul 25.

Abstract

Conjunctivitis is an uncommon finding in commercial swine herds, and the etiology of the disease is rarely studied. We investigated cases of conjunctivitis in 3 wean-to-finish swine farms. Eye swabs and tissues were obtained from clinically affected pigs (8-22 wk of age), from unaffected pigs in contact with affected pen-mates, and from age-matched pigs from an unaffected herd. Real-time PCR (rtPCR) testing for demonstrated consistent detection and high bacterial load in samples from affected herds (clinically affected animals and non-clinical pen-mates). Ct values in affected pigs were 18.9-25.3; values were 36.4-38.6 in unaffected pigs from unaffected herds. Additionally, was identified within inflamed palpebral conjunctivae by in situ hybridization. The association of rtPCR and in situ detection of , along with the lack of detection of other potential pathogens and noninfectious causes, suggests the involvement of in the etiology and pathogenesis of the reported swine conjunctivitis.

摘要

结膜炎在商品猪群中并不常见,且该病的病因很少被研究。我们调查了3个断奶至育肥猪场的结膜炎病例。从临床受影响的猪(8至22周龄)、与受影响同栏猪接触的未受影响猪以及来自未受影响猪群的年龄匹配猪中采集眼拭子和组织。对[具体病原体]进行的实时PCR(rtPCR)检测显示,在受影响猪群(临床受影响动物和非临床同栏猪)的样本中检测结果一致且细菌载量高。受影响猪的Ct值为18.9至25.3;来自未受影响猪群的未受影响猪的Ct值为36.4至38.6。此外,通过原位杂交在发炎的睑结膜中鉴定出了[具体病原体]。rtPCR与[具体病原体]的原位检测结果相关,同时未检测到其他潜在病原体和非感染性病因,这表明[具体病原体]参与了所报道的猪结膜炎的病因和发病机制。

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