Intestinal Imaging Centre, St Mark's Hospital, Harrow, Middlesex, UK.
Clin Radiol. 2010 Feb;65(2):126-32. doi: 10.1016/j.crad.2009.09.011. Epub 2009 Dec 3.
To investigate performance of computed-assisted detection (CAD)-assisted radiographers interpreting computed tomography colonography (CTC) in routine practice.
Three hundred and three consecutive symptomatic patients underwent CTC. Examinations were double-read by trained radiographers using primary two-dimensional/three-dimensional (2D/3D) analysis supplemented by "second reader" CAD. Radiographers recorded colonic neoplasia, interpretation times, and patient management strategy code (S0, inadequate; S1, normal; S2, 6-9 mm polyp; S3, > or = 10 mm polyp; S4, cancer; S5, diverticular stricture) for each examination. Strategies were compared to the reference standard using kappa statistic, interpretation times using paired t-test, learning curves using logistic regression and Pearson's correlation coefficient.
Of 303 examinations, 69 (23%) were abnormal. CAD-assisted radiographers detected 17/17 (100%) cancers, 21/28 (72%) polyps > or = 10 mm and 42/60 (70%) 6-9 mm polyps. The overall agreement between radiographers and the reference management strategy was good (kappa 0.72; CI: 0.65, 0.78) with agreement for S1 strategy in 189/211 (90%) exams; S2 in 19/27 (70%); S3 in 12/19 (63%); S4 in 17/17 (100%); S5 in 5/6 (83%). The mean interpretation time was 17 min (SD = 11) compared with 8 min (SD = 3.5) for radiologists. There was no learning curve for recording correct strategies (OR 0.88; p = 0.12) but a significant reduction in interpretation times, mean 14 and 31 min (last/first 50 exams; -0.46; p < 0.001).
Routine CTC interpretation by radiographers is effective for initial triage of patients with cancer, but independent reporting is currently not recommended.
研究计算机辅助检测(CAD)辅助放射科医师在常规实践中解读计算机断层结肠成像(CTC)的性能。
303 例有症状的连续患者接受 CTC 检查。经过培训的放射科医师使用二维/三维(2D/3D)分析对其进行了双次读取,并通过“第二读者”CAD 进行了补充。放射科医师记录了每例检查的结肠肿瘤、解释时间和患者管理策略代码(S0,不足;S1,正常;S2,6-9mm 息肉;S3,≥10mm 息肉;S4,癌症;S5,憩室狭窄)。使用 Kappa 统计、配对 t 检验、逻辑回归和 Pearson 相关系数比较了这些策略与参考标准的差异。
在 303 次检查中,有 69 次(23%)为异常。CAD 辅助放射科医师检测到 17/17(100%)癌症、21/28(72%)≥10mm 息肉和 42/60(70%)6-9mm 息肉。放射科医师与参考管理策略之间的总体一致性较好(kappa 值为 0.72;置信区间:0.65,0.78),189/211(90%)检查的 S1 策略一致;27/27(70%)的 S2 策略一致;19/19(63%)的 S3 策略一致;17/17(100%)的 S4 策略一致;6/6(83%)的 S5 策略一致。平均解释时间为 17 分钟(标准差=11),而放射科医生的解释时间为 8 分钟(标准差=3.5)。记录正确策略的学习曲线没有意义(OR 0.88;p=0.12),但解释时间显著缩短,平均 14 分钟和 31 分钟(最后/最初 50 次检查;-0.46;p<0.001)。
放射科医师对 CTC 进行常规解读,对癌症患者的初步分诊是有效的,但目前不建议独立报告。