National Center for AIDS/STD Control and Prevention, Beijing, People's Republic of China.
J Acquir Immune Defic Syndr. 2010 Feb;53 Suppl 1:S66-73. doi: 10.1097/QAI.0b013e3181c7db43.
To assess HIV and syphilis infection among men who have sex with men (MSM) in Chinese regions with historically low HIV prevalence.
A cross-sectional survey was conducted in 20 cities or districts across 4 provinces, 2 autonomous regions, and a municipality. Socioeconomic/behavioral risk factors were measured. Blood samples were tested for HIV via enzyme-linked immunosorbent assay and Western blot confirmation and syphilis via rapid plasma reagin and passive particle agglutination test for detection of Treponema pallidum Antibodies.
Of 4983 MSM participants, 2.9% were HIV infected (range: 0%-15.1%) and 9.8% were syphilis infected (1.3%-29.3%). Syphilis infection was associated with older age [adjusted odds ratio (AOR) = 2.9; 95% confidence interval (CI): 2.0 to 4.3], not being married or cohabiting (AOR = 0.7; 95% CI: 0.5-0.9), less education (AOR = 1.3; 95% CI: 1.0 to 1.7), inconsistent condom use during anal sex with men (AOR = 1.4; 95% CI: 1.0 to 1.8), and living in inner Mongolia (AOR = 23.9; 95% CI: 9.7 to 58.6), Jilin (AOR = 7.9; 95% CI: 3.4 to 18.3), Heilongjiang (AOR = 7.1; 95% CI: 3.1 to 16.6), Liaoning (AOR = 6.1; 95% CI: 2.6 to 14.2), or Chongqing (AOR = 5.9; 95% CI: 2.5 to 13.9). HIV infection was associated with older age (AOR = 3.7; 95% CI: 2.0 to 6.7), less education (AOR = 2.9; 95% CI: 1.8 to 4.7), inconsistent condom use during anal sex with men (AOR = 1.9; 95% CI: 1.2 to 3.2), syphilis infection (AOR = 2.1; 95% CI: 1.3 to 3.4), and living either in Liaoning (AOR = 8.2; 95% CI: 1.1 to 61.4) or Chongqing (AOR = 57.2; 95% CI: 7.9 to 414.4).
HIV and syphilis have reached alarming rates in China's MSM population, thus, appropriate responses are urgently needed.
评估中国低 HIV 流行地区男男性行为者（MSM）中的 HIV 和梅毒感染情况。
在 4 个省、2 个自治区和 1 个直辖市的 20 个城市或地区进行了横断面调查。测量了社会经济/行为风险因素。通过酶联免疫吸附试验和 Western blot 确认检测 HIV，通过快速血浆反应素和被动颗粒凝集试验检测梅毒，检测梅毒螺旋体抗体。
4983 名 MSM 参与者中，有 2.9%（范围：0%-15.1%）感染了 HIV，9.8%（1.3%-29.3%）感染了梅毒。梅毒感染与年龄较大有关（调整后的优势比[OR] = 2.9；95%置信区间[CI]：2.0 至 4.3）、未婚或同居（OR = 0.7；95%CI：0.5-0.9）、受教育程度较低（OR = 1.3；95%CI：1.0 至 1.7）、与男性进行肛交时避孕套使用不一致（OR = 1.4；95%CI：1.0 至 1.8）、以及居住在内蒙古（OR = 23.9；95%CI：9.7 至 58.6）、吉林（OR = 7.9；95%CI：3.4 至 18.3）、黑龙江（OR = 7.1；95%CI：3.1 至 16.6）、辽宁（OR = 6.1；95%CI：2.6 至 14.2）或重庆（OR = 5.9；95%CI：2.5 至 13.9）。HIV 感染与年龄较大有关（OR = 3.7；95%CI：2.0 至 6.7）、受教育程度较低（OR = 2.9；95%CI：1.8 至 4.7）、与男性进行肛交时避孕套使用不一致（OR = 1.9；95%CI：1.2 至 3.2）、梅毒感染（OR = 2.1；95%CI：1.3 至 3.4）以及居住在辽宁（OR = 8.2；95%CI：1.1 至 61.4）或重庆（OR = 57.2；95%CI：7.9 至 414.4）。
HIV 和梅毒在中国 MSM 人群中已达到令人震惊的水平，因此急需采取适当措施。
